Wasiutyński A
Pol Med Sci Hist Bull (1973). 1976 Apr-Jun;15(2):161-8.
The investigations were performed on 15 dogs with experimental uremia, but free of overhydration and circulatory insufficiency. Parahilar lungs areas showed numerous atelectatic foci, the peripheral part--conpensatory marginal emphusema. Light microscopy revealed a decreased number of granular cells, electron microscopy the "empty" appearance of the lamellar structures, and decrease or absence of the Hale-positive layer of alveolar lining film. The inhibition of cells controlling the alveolar surgace tension seems to be crucial in the pathomechanism of development of uremic lung lesions.
对15只患有实验性尿毒症但无水分过多和循环功能不全的狗进行了研究。肺门旁区域可见大量肺不张灶，外周部分为代偿性边缘性肺气肿。光镜显示颗粒细胞数量减少，电镜显示板层结构呈“空泡”样外观，肺泡内衬膜的黑尔阳性层减少或缺失。控制肺泡表面张力的细胞受到抑制似乎在尿毒症性肺病变发展的发病机制中起关键作用。
