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[体外循环胶体渗透压的初步研究]

[Preliminary study of colloid osmotic pressure for cardiopulmonary bypass].

作者信息

Wang D, Xiang L, Luo J

机构信息

Department of Cardiovascular Surgery, General Hospital of People's Liberation Army, Beijing.

出版信息

Zhonghua Wai Ke Za Zhi. 1996 Dec;34(12):751-3.

PMID:9590779
Abstract

The ideal colloid osmotic pressure is beneficial to decrease the fluid accumulated in the pulmonary and other tissue during cardiopulmonary bypass. Schupbach reported the proper colloidosmotic pressure for cardiopulmonary bypass was 2.1 kPa (16 mmHg). Colloid osmotic pressures of blood and priming fluid during cardiopulmonary bypass were measured in 28 patients with heart disease by using colloid osmotic pressure detection apparatus. The value of colloid osmotic pressure suitable for the designed standard was apparently different among the Gelofusine group and other groups. P value was 0.005. Priming fluid for cardiopulmonary bypass needs to satisfy the quality and the quantity of colloid osmotic pressure. Using Albumin isn't economical. Whole blood and plazma are not suitable for increasing colloid osmotic pressure. Hydroxyethyl starch or Gelofusine is best choice in priming to get designed standard of colloid osmotic pressure. The ratio of hydroxyethyl starch or Gelofusine in priming fluid should beyond 1/2.

摘要

理想的胶体渗透压有利于减少体外循环期间肺及其他组织中积聚的液体。舒普巴赫报告称,体外循环的合适胶体渗透压为2.1千帕(16毫米汞柱)。采用胶体渗透压检测装置对28例心脏病患者体外循环期间的血液和预充液胶体渗透压进行了测量。佳乐施组与其他组之间适合设计标准的胶体渗透压值明显不同。P值为0.005。体外循环预充液需要满足胶体渗透压的质量和数量要求。使用白蛋白不经济。全血和血浆不适合用于提高胶体渗透压。羟乙基淀粉或佳乐施是预充时达到设计胶体渗透压标准的最佳选择。预充液中羟乙基淀粉或佳乐施的比例应超过1/2。

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