Xu S, Wang P, Li Z
Second Affiliated Hospital, Zhejiang Medical University, Hangzhou.
Zhonghua Wai Ke Za Zhi. 1996 Jul;34(7):424-6.
Hashimoto's disease associated with thyroid cancer is not common. From January 1976 to December 1994, a total of 95 patients with Hashimoto's disease were treated surgically. Six (5 Papillary 1 folicular) of 95 patients had thyroid cancer which was concomitantly revealed pathologically. They were all women with mean age of 30.3 years. The size of tumor was 0.3-2.0 cm. Follow-up for 1-17 years showed that they were all alive and healthy. Two patients were misdiagnosed as having anaplastic carcinoma but the definitive diagnosis by immunohistochemical analysis was thyroid malignant lymphoma (B-cell type). Hashimoto's disease and thyroid cancer relationship, diagnosis, and treatment are discussed.
桥本氏病合并甲状腺癌并不常见。1976年1月至1994年12月，共有95例桥本氏病患者接受了手术治疗。95例患者中有6例（5例乳头状癌、1例滤泡状癌）术中病理检查同时发现甲状腺癌。她们均为女性，平均年龄30.3岁。肿瘤大小为0.3 - 2.0厘米。随访1 - 17年显示，她们均存活且健康。2例患者曾被误诊为间变性癌，但免疫组化分析确诊为甲状腺恶性淋巴瘤（B细胞型）。本文讨论了桥本氏病与甲状腺癌的关系、诊断及治疗。
