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兔股骨中的钛植入物:组织学评估。

Titanium implants in rabbit femur: a histologic evaluation.

作者信息

Nociti Júnior F H, Sallum A W, Sallum E A, Bozzo L

机构信息

Departamento de Prótese/Periodontia, Faculdade de Odontologia de Piracicaba, UNICAMP, Brasil.

出版信息

Braz Dent J. 1997;8(2):105-11.

PMID:9590934
Abstract

The success achieved by Scandinavian researchers in the development of long-term implants has stimulated many dentists to apply them worldwide. However, most of the implants did not have sufficient scientific support. The purpose of this study was to evaluate host tissue response to the insertion of an endosseous dental implant. Twenty adult New Zealand rabbits were used. Histological evaluation was prepared from the femurs. Results showed a hemorrhagic aspect and inflammatory infiltration which was subsequently substituted by granulation tissue, and later, formation of bone tissue. In the cortical bone, the presence of a necrotic area was observed which was later remodelled, and also an intense proliferation of endosteum and periosteum in the regions next to the implant, resulting in a thickening of the cortical bone surface close to the implant. Therefore, it was observed that titanium implants (Carbontec-Special Materials Ltda.) did not interfere with the bone healing process.

摘要

斯堪的纳维亚研究人员在长期植入物开发方面取得的成功促使许多牙医在全球范围内应用它们。然而,大多数植入物没有足够的科学依据。本研究的目的是评估宿主组织对骨内牙种植体植入的反应。使用了20只成年新西兰兔。从股骨制备组织学评估。结果显示有出血现象和炎症浸润,随后被肉芽组织取代,之后形成骨组织。在皮质骨中,观察到有一个坏死区域,该区域后来被重塑,并且在植入物旁边的区域骨内膜和骨膜有强烈增殖,导致靠近植入物的皮质骨表面增厚。因此,可以观察到钛植入物(Carbontec-Special Materials Ltda.)不会干扰骨愈合过程。

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Titanium implants in rabbit femur: a histologic evaluation.兔股骨中的钛植入物:组织学评估。
Braz Dent J. 1997;8(2):105-11.
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引用本文的文献

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Transcription factor and bone marrow stromal cells in osseointegration of dental implants.转录因子与骨髓基质细胞在牙种植体骨整合中的作用
Eur Cell Mater. 2013 Dec 19;26:263-70; discussion 270-1. doi: 10.22203/ecm.v026a19.