Asikainen P, Klemetti E, Kotilainen R, Vuillemin T, Sutter F, Voipio H M, Kullaa A
Department of Oral and Dental Diseases, Faculty of Medicine, University of Kuopio, Finland.
Clin Oral Implants Res. 1998 Feb;9(1):20-5. doi: 10.1034/j.1600-0501.1998.090103.x.
Construction of different kinds of prostheses on irradiated bone tissues after tumour surgery is a complicated part of modern implantology. In irradiated regions of the jaws where the bone layers are thin and the blood supply also is minimal, knowledge of the impact of each dose of radiation is very important. The aim of this study was to compare the bone response around titanium implants loaded with fixed bridges in dog mandibles irradiated with total doses of 40, 50 or 60 Gy. The results suggest that after irradiation with 40-50 Gy, when the dose is fractioned in order to achieve higher tolerance of the tissues compared with single dose irradiation, titanium implants may become osseointegrated in the mandibles. For high success rates, however, careful planning of radiotherapy and selection of implantation site with an adequate blood supply are essential.
肿瘤手术后在受辐照骨组织上构建不同类型的假体是现代植入学中复杂的一部分。在颌骨的辐照区域，骨层薄且血液供应极少，了解每次辐射剂量的影响非常重要。本研究的目的是比较在接受40、50或60 Gy总剂量辐照的犬下颌骨中，加载固定桥的钛植入物周围的骨反应。结果表明，在40 - 50 Gy辐照后，当剂量分次给予以实现与单次剂量辐照相比更高的组织耐受性时，钛植入物可能在下颌骨中实现骨整合。然而，为了获得高成功率，精心规划放射治疗和选择具有充足血液供应的植入部位至关重要。
