Alexander W D, Wensley R T, Price G, Hartog M
Postgrad Med J. 1976 May;52(607):251-3. doi: 10.1136/pgmj.52.607.251.
This study was performed to assess the effect of chlorpropamide therapy on the fibrinolytic activity of blood of maturity onset diabetics. Normal controls were also studied and the results compared with diabetics. Diabetics were found to have deficient fibrinolytic activity compared with non-diabetics but chlorpropamide did not appear significantly to affect this deficiency either in males or females when given therapeutically over a 6-month period.
本研究旨在评估氯磺丙脲治疗对成年型糖尿病患者血液纤溶活性的影响。同时对正常对照组进行了研究，并将结果与糖尿病患者进行比较。结果发现，与非糖尿病患者相比，糖尿病患者的纤溶活性不足，但在为期6个月的治疗过程中，给予氯磺丙脲治疗后，无论是男性还是女性，该药物似乎均未对这种纤溶活性不足产生显著影响。
