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Chlorpropamide and fibrinolytic activity in maturity onset diabetes mellitus.

作者信息

Alexander W D, Wensley R T, Price G, Hartog M

出版信息

Postgrad Med J. 1976 May;52(607):251-3. doi: 10.1136/pgmj.52.607.251.

Abstract

This study was performed to assess the effect of chlorpropamide therapy on the fibrinolytic activity of blood of maturity onset diabetics. Normal controls were also studied and the results compared with diabetics. Diabetics were found to have deficient fibrinolytic activity compared with non-diabetics but chlorpropamide did not appear significantly to affect this deficiency either in males or females when given therapeutically over a 6-month period.

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1
FIBRINOLYTIC ACTIVITY IN DIABETES MELLITUS.
Scott Med J. 1964 Sep;9:359-64. doi: 10.1177/003693306400900901.
2
PHARMACOLOGICAL ENCHANCEMENT OF FIBRINOLYTIC ACTIVITY OF BLOOD.
J Clin Pathol. 1964 May;17(3):328-32. doi: 10.1136/jcp.17.3.328.
5
The effects of chlorpropamide on intermittent claudication and fibrinolysis.
Lancet. 1962 Jun 9;1(7241):1213-5. doi: 10.1016/s0140-6736(62)92255-9.
7
Reduction of blood fibrinolytic activity in diabetes mellitus by insulin.
Lancet. 1959 Dec 12;2(7111):1067. doi: 10.1016/s0140-6736(59)91534-x.
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Effect of the sulphonylureas on fibrinolysis.
Lancet. 1960 Sep 17;2(7151):622-5. doi: 10.1016/s0140-6736(60)91694-9.

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