Krasil'nikov O V, Da Cruz J B, Nogueira R A
Institute of Physiology and Biophysics, Tashkent, Uzbekistan.
Biofizika. 1998 Mar-Apr;43(2):299-303.
The channel formed by colicin Ia in planar lipid bilayer was used to develop a method determining a diameter of each channel entrance. The method is based on measuring of a channel filling with nonelectrolytes through cis- and trans-entrance separately. To do this, one need to establish the two things only: the conductance of an ion channel and the conductivity of used solutions. Using the method to predict the internal geometry of a channel lumen is discussed.
利用大肠菌素Ia在平面脂质双分子层中形成的通道开发了一种确定每个通道入口直径的方法。该方法基于分别通过顺式和反式入口测量通道对非电解质的填充情况。为此，仅需确定两件事：离子通道的电导和所用溶液的电导率。还讨论了使用该方法预测通道内腔内部几何形状的情况。
