al Dousary S, Attallh M, al Rabah A, al Ammar A, Gaafar M
Department of Otolaryngology, Head and Neck Surgery, King Abdul Aziz University Hospital, Riyadh, King Saud University.
Otolaryngol Pol. 1998;52(1):19-22.
Otitis externa malignant (OEM) is a virulent infection if it is not diagnosed and treated promptly. Its mortality rate was reported to be 53% when there is associated facial nerve paralysis. It usually affects elderly diabetic patients, who present with deep-seated pain and other features of non-resolving otitis externa. It is mostly caused by Pseudomonas (P) aeruginosa and the treatment of choice is anti-Pseudomonas antibiotic. A 64-year-old diabetic male patient is described who presented with left ear pain and discharge for two months and did not respond to ordinary treatment. The patient also noticed a progressive facial weakness on the same side. The clinical presentation, investigations, treatment and follow-up of the OEM are discussed on the basis of our case and the review of the literature. The diagnosis of OEM is based on high index of suspicion and confirmed by histopathologic changes and radionuclide studies. Gallium 67 citrate scan is a sensitive way to diagnose and follow up the regression of the disease in response to the medical treatment. Ciprofloxacin is the treatment of choice; however, it has to be in accordance to culture and sensitivity results.
恶性外耳道炎(OEM)若不及时诊断和治疗,是一种严重的感染。据报道,伴有面神经麻痹时其死亡率为53%。它通常影响老年糖尿病患者,这些患者表现为深部疼痛及其他外耳道炎不愈的症状。其主要由铜绿假单胞菌(P)引起,治疗的首选药物是抗铜绿假单胞菌抗生素。本文描述了一名64岁的糖尿病男性患者,他左耳疼痛、流脓两个月,对常规治疗无反应。患者还注意到同侧面部逐渐出现无力症状。基于我们的病例及文献复习,讨论了OEM的临床表现、检查、治疗及随访。OEM的诊断基于高度的怀疑指数,并通过组织病理学改变和放射性核素研究得以证实。枸橼酸镓67扫描是诊断和随访疾病对治疗反应消退情况的一种敏感方法。环丙沙星是首选治疗药物;然而,必须根据培养和药敏结果来使用。