Reardon M J, Oury J H
Baylor College of Medicine and The Methodist Hospital, Houston, TX 77030, USA.
Curr Opin Cardiol. 1998 Mar;13(2):85-90. doi: 10.1097/00001573-199803000-00003.
Allograft valves have been used for aortic valve replacement (AVR) for 35 years with excellent results. Early attempts at mitral valve replacement (MVR) with mitral valve allograft were unsuccessful mainly due to technical issues of measurement of appropriate graft size, difficulty of reimplantation, and early dehiscence of the papillary muscle anastomosis. Recently, interest in this procedure has been rekindled by successful laboratory experiments with mitral valve allograft implantation and improved understanding of the mitral valve apparatus from extensive mitral valve repair experience. In this article, we discuss the rationale for allograft use, the historical perspective of allograft use, and technical problems, along with current solutions and clinical outcomes of MVR with mitral valve allograft. Tricuspid valve replacement (TVR) with allograft mitral valve also is briefly discussed.
同种异体瓣膜用于主动脉瓣置换术（AVR）已有35年，效果良好。早期尝试用二尖瓣同种异体瓣膜进行二尖瓣置换术（MVR）未成功，主要是由于合适移植物大小的测量技术问题、再植入困难以及乳头肌吻合口早期裂开。最近，二尖瓣同种异体瓣膜植入的成功实验室实验以及从广泛的二尖瓣修复经验中对二尖瓣装置的更好理解，重新燃起了人们对该手术的兴趣。在本文中，我们讨论了使用同种异体瓣膜的理论依据、同种异体瓣膜使用的历史背景、技术问题，以及二尖瓣同种异体瓣膜MVR的当前解决方案和临床结果。还简要讨论了用同种异体二尖瓣进行三尖瓣置换术（TVR）。
