Ota H, Sannan H, Taoka K, Uji Y
Department of Ophthalmology, National Tsu Hospital, Japan.
Nippon Ganka Gakkai Zasshi. 1998 Apr;102(4):276-80.
We report 4 fullterm newborns who developed retinopathy similar to oxygen-induced retinopathy after high concentration oxygen therapy for pneumothorax and emphysema. Two of them had a severe condition, showing marked dilatation, winding, and abnormal branching of the retinal vessels, especially veins, and retinal trubidity. Comparison between the 4 patients and controls without such retinopathy suggested that factors such as the oxygen concentration, the duration of oxygen therapy, the gradual reduction method, and the high level and changes in PaO2 were involved in the development of the retinopathy. Even in fullterm infants, treatment should be performed with consideration of the possible occurrence of changes in the eye fundus.
我们报告了4例足月儿，他们在接受高浓度氧疗治疗气胸和肺气肿后，出现了类似于氧诱导性视网膜病变的视网膜病变。其中2例病情严重，表现为视网膜血管，尤其是静脉明显扩张、迂曲和分支异常，以及视网膜混浊。将这4例患者与无此类视网膜病变的对照组进行比较表明，氧浓度、氧疗持续时间、逐渐降低方法以及动脉血氧分压（PaO2）的高水平和变化等因素与视网膜病变的发生有关。即使是足月儿，治疗时也应考虑到眼底可能出现变化。
