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[参与拉丁美洲围产医学协作中心(ECLAMC)的10家智利产科医院的先天性畸形发病率。三个时期(1971 - 1977年、1982 - 1988年、1989 - 1994年)的比较]

[Incidence of congenital malformations in 10 Chilean maternity hospitals that participate in the ECLAMC. Comparison of 3 periods (1971-1977, 1982-1988, 1989-1994)].

作者信息

Nazer J, Cifuentes L, Meza M

机构信息

Unidad de Maternidad, Hospital Clínico Universidad de Chile, Santiago, Chile.

出版信息

Rev Med Chil. 1997 Sep;125(9):993-1001.

PMID:9595789
Abstract

BACKGROUND

The Latin American Collaborative Study of Congenital Malformations is an epidemiological surveillance system for congenital malformations that operates in 11 Latin American Countries.

AIM

To report the incidence of congenital malformations in 8 Chilean maternity hospitals participating in this study, between 1989 and 1994.

MATERIAL AND METHODS

During the study period, 133,564 newborns and 1,196 stillbirths from 8 Chilean maternity hospitals were examined. These results were compared with those of a similar survey performed in 1982-1988.

RESULTS

The proportion of stillbirths in the study period was 0.88%. There were 3,268 malformed newborns (2.42%) and 125 malformed stillbirths (10.45%). These proportion of malformations among newborns were lower and among stillbirths were higher than those reported for the rest of Latin American countries. When comparing the results with the previous survey, a reduction in the proportion of malformations among newborns was observed. However, in all Latin American countries, the prevalence of malformations in newborns and stillbirths increased in this period. In the period 1969-1995, in one Chilean hospital, maternal ages and the proportion of congenital malformation showed parallel and rising curves.

CONCLUSIONS

This survey shows some differences in the prevalence of congenital malformations, when the figures are compared with other Latin American countries and with previous surveys.

摘要

背景

拉丁美洲先天性畸形协作研究是一个在11个拉丁美洲国家开展的先天性畸形流行病学监测系统。

目的

报告1989年至1994年期间参与本研究的8家智利妇产医院先天性畸形的发病率。

材料与方法

在研究期间,对来自8家智利妇产医院的133,564例新生儿和1,196例死产儿进行了检查。将这些结果与1982 - 1988年进行的类似调查结果进行了比较。

结果

研究期间死产儿的比例为0.88%。有3,268例畸形新生儿(2.42%)和125例畸形死产儿(10.45%)。新生儿中畸形的比例低于拉丁美洲其他国家报告的比例,而死产儿中畸形的比例高于其他国家。将结果与之前的调查进行比较时,观察到新生儿中畸形比例有所下降。然而,在所有拉丁美洲国家,这一时期新生儿和死产儿中畸形的患病率均有所上升。在1969 - 1995年期间,在一家智利医院,产妇年龄与先天性畸形比例呈平行上升曲线。

结论

与其他拉丁美洲国家以及之前的调查相比,本次调查显示先天性畸形患病率存在一些差异。

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