Verma O P, Prasad B K, Slaughter J
Prostaglandins. 1976 Aug;12(2):217-27. doi: 10.1016/0090-6980(76)90117-9.
Oviduct segments from infundibulum, magnum, uterus, utero-vaginal junction and vagina of actively laying hens at preoviposition time were tested for their contractile reaction to prostaglandin E1 by in vitro or in vivo methods. Maximum stimulatory response was observed from the muscular strips of the proximal oviduct segment (infundibulum) and a complete relaxation was recorded from the distal part (vagina) at molar concentrations of 1.4 X 10(-7), 3.4 X 10(-7) and 7.0 X 10(-7). The uterine strips reacted with a stimulatory response at higher concentrations (1.4 X 10(-6) and 2.8 X 10(-6) moles), but lacked any significant change at lower concentrations. The uterovaginal muscular strips showed a mild but prolonged inhibitory response, while the magnum responded with a significant increase in the luminal pressure when tested in vivo. It is concluded that PGE1 exerts a stimulatory effect on the uterus to initiate transport of the egg to subsequent segments (utero-vaginal junction and vagina), which relax under PGE1 influence and allow passage of the egg by pressure differences.
在产蛋前，通过体外或体内方法测试了处于产蛋高峰期的母鸡的漏斗部、膨大部、子宫、子宫阴道连接处和阴道的输卵管节段对前列腺素E1的收缩反应。在摩尔浓度为1.4×10^(-7)、3.4×10^(-7)和7.0×10^(-7)时，观察到近端输卵管节段（漏斗部）的肌肉条有最大刺激反应，而远端部分（阴道）则记录到完全松弛。子宫条在较高浓度（1.4×10^(-6)和2.8×10^(-6)摩尔）时产生刺激反应，但在较低浓度时没有任何显著变化。子宫阴道肌肉条显示出轻微但持续的抑制反应，而膨大部在体内测试时管腔内压力显著升高。结论是，前列腺素E1对子宫产生刺激作用，启动卵子向后续节段（子宫阴道连接处和阴道）的运输，这些节段在前列腺素E1的影响下松弛，并通过压力差使卵子通过。
