ten Koppel P G, van Osch G J, Verwoerd C D, Verwoerd-Verhoef H L
Department of Otorhinolaryngology, Head and Neck Surgery, Erasmus University Medical Center Rotterdam, The Netherlands.
Int J Pediatr Otorhinolaryngol. 1998 Feb;43(1):1-10. doi: 10.1016/s0165-5876(97)00141-9.
Injury-induced abnormal development of the cricoid ring has been demonstrated in previous growth studies. In this study we focused on the immediate effects of various types of lesions to the cricoid, eliminating the influence of inserting muscles. In isolated, vital cricoids (cricoid explants) the anterior arch was split, creating a small gap between the cut ends. Previous injury to the internal surface of the cricoid ring resulted in a three to four fold increase of the diameter of the gap, actually widening the interrupted cricoid. On the contrary, injuring the external surface of the cricoid cartilage prior to anterior cricoid split, leads to an overlap of the cut edges, and a narrowing of the ring. These injury-specific changes in shape of the cricoid ring are ascribed to the release of interlocked stresses, present in the cartilage. It is suggested that the demonstrated methods to change the shape of the cricoid ring in a predictable way, are relevant for the treatment of patients with cricoid malformation.
在以往的生长研究中已证实，损伤会导致环状软骨环异常发育。在本研究中，我们聚焦于各种类型的环状软骨损伤的即时效应，排除了插入肌肉的影响。在分离的、有活力的环状软骨（环状软骨外植体）中，将前弓劈开，在断端之间形成一个小间隙。先前环状软骨环内表面的损伤导致间隙直径增加三到四倍，实际上使中断的环状软骨变宽。相反，在环状软骨前劈开之前损伤环状软骨的外表面，会导致断端边缘重叠，环状软骨变窄。环状软骨环形状的这些损伤特异性变化归因于软骨中存在的互锁应力的释放。有人提出，所展示的以可预测方式改变环状软骨环形状的方法，与环状软骨畸形患者的治疗相关。
