Zubler J, Markowski G, Yale S, Graham R, Rosenthal T C
Department of Pediatrics, State University of New York, Buffalo 14215, USA.
Arch Fam Med. 1998 May-Jun;7(3):230-3. doi: 10.1001/archfami.7.3.230.
Improved access to less invasive testing has resulted in more Americans being diagnosed with asymptomatic gallstones. The family physician has had to rely on community-based or referral patient studies to advise their office-based patients about treatment options.
To understand the natural history of asymptomatic gallstones discovered through a routine patient care process in a rural, office-based research network of 9 family physician practices.
Nine family physician practices agreed to comb their records for medical records of patients found to have asymptomatic gallstones during their routine primary care practice. Medical records were then reviewed annually for 5 years for evidence of gallstone-related problems Results were compared with previous English-language literature studies.
Asymptomatic gallstones were found in 32 patients (19 women [59%] and 13 men [41%] with an average age of 59.5 years). Symptoms developed in 8 patients (25%) after an average latency period of 3 years 5 months. Seven patients underwent cholecystectomy; there was no gallstone-related mortality in this group. One patient who developed a ruptured gallbladder required an emergency procedure.
Routine office practice is detecting only a small percentage of the asymptomatic gallstones expected by community-based screening studies. While more of these patients became symptomatic than in general population studies, most patients with asymptomatic gallstones required no treatment. Those patients in family practice offices who are serendipitously found to have gallstones can generally be followed up conservatively.
获得侵入性较小的检测方法的机会增加,导致更多美国人被诊断出患有无症状胆结石。家庭医生不得不依靠基于社区的或转诊患者研究,为其门诊患者提供治疗选择方面的建议。
了解在一个由9个家庭医生诊所组成的农村门诊研究网络中,通过常规患者护理过程发现的无症状胆结石的自然病史。
9个家庭医生诊所同意梳理他们的记录,以查找在其常规初级保健实践中被发现患有无症状胆结石的患者的病历。然后对病历进行为期5年的年度审查,以寻找与胆结石相关问题的证据。将结果与以前的英文文献研究进行比较。
在32名患者(19名女性[59%]和13名男性[41%],平均年龄59.5岁)中发现了无症状胆结石。8名患者(25%)在平均3年5个月的潜伏期后出现了症状。7名患者接受了胆囊切除术;该组中没有与胆结石相关的死亡病例。1名出现胆囊破裂的患者需要进行紧急手术。
常规门诊实践仅检测到基于社区筛查研究预期的无症状胆结石的一小部分。虽然这些患者中出现症状的比一般人群研究中的更多,但大多数无症状胆结石患者不需要治疗。在家庭医生诊所中偶然发现患有胆结石的患者通常可以进行保守随访。