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不同雌激素治疗方案对抗凝血酶III水平的影响。

Effect of various estrogen treatment schedules on antithrombin III levels.

作者信息

Ambrus J L, Ambrus C M, Lillie M A, Browne B J, Hanson F W, Niswander K, Witul M, Jung O S, Bartfay-Szabo A

出版信息

Res Commun Chem Pathol Pharmacol. 1976 Jul;14(3):543-9.

PMID:959656
Abstract

Antithrombin III levels were determined in 18 normal indiviuals of both sexes, 24 pregnant women (at term), 20 patients treated with oral contraceptives and 21 postmenopausal patients treated with Premarin. There was no sex difference in antithrombin III levels in the untreated control group. Pregnant women at term had the lowest levels of antithrombin III. The second lowest values were exhibited by women on oral contraceptives. Both of these groups differed significantly (p less than 0.05) from the controls. Premarin treated postmenopausal women had somewhat lower levels of antithrombin III than controls but these were statistically not significant.

摘要

测定了18名正常男女、24名足月孕妇、20名口服避孕药治疗的患者以及21名用普雷马林治疗的绝经后患者的抗凝血酶III水平。在未治疗的对照组中,抗凝血酶III水平无性别差异。足月孕妇的抗凝血酶III水平最低。口服避孕药的女性抗凝血酶III水平次之。这两组与对照组均有显著差异(p小于0.05)。用普雷马林治疗的绝经后女性的抗凝血酶III水平略低于对照组,但在统计学上无显著差异。

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