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扁桃体切除术和腺样体切除术的临床试验:现有研究的局限性及当前对疗效评估的努力

Clinical trials of tonsillectomy and adenoidectomy: limitations of existing studies and a current effort to evaluate efficacy.

作者信息

Paradise J L

出版信息

South Med J. 1976 Aug;69(8):1049-53. doi: 10.1097/00007611-197608000-00030.

DOI:10.1097/00007611-197608000-00030
PMID:959872
Abstract

Indications for tonsillectomy and adenoidectomy (T&A) are both uncertain and controversial. Only five prospective clinical trials of T&A have been reported. These studies provided important data, but failed to test the efficacy of the procedures in children most affected by tonsil- and adenoid-related conditions. A study currently under way focuses on just such children and also explores related immunologic issues.

摘要

扁桃体切除术和腺样体切除术(T&A)的适应症既不明确也存在争议。仅报道了五项关于T&A的前瞻性临床试验。这些研究提供了重要数据,但未能在受扁桃体和腺样体相关疾病影响最严重的儿童中测试该手术的疗效。目前正在进行的一项研究聚焦于此类儿童,并探讨相关的免疫学问题。

相似文献

1
Clinical trials of tonsillectomy and adenoidectomy: limitations of existing studies and a current effort to evaluate efficacy.扁桃体切除术和腺样体切除术的临床试验:现有研究的局限性及当前对疗效评估的努力
South Med J. 1976 Aug;69(8):1049-53. doi: 10.1097/00007611-197608000-00030.
2
[Acute recurrent pharyngotonsillitis and otitis media].[急性复发性咽扁桃体炎和中耳炎]
Acta Otorhinolaryngol Ital. 2006 Oct;26(5 Suppl 84):30-55.
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Role of adenotonsillectomy in the management of pediatric ear, nose and throat infections.腺样体扁桃体切除术在小儿耳鼻喉感染治疗中的作用
Pediatr Infect Dis J. 1994 Jan;13(1 Suppl 1):S75-8; discussion S78-9. doi: 10.1097/00006454-199401001-00016.
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Indications for tonsillectomy and adenoidectomy.
Am Fam Physician. 1991 Nov;44(5):1639-46.
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Tonsils and adenoids. When is surgery indicated?扁桃体和腺样体。何时需要进行手术?
Prim Care. 1982 Jun;9(2):355-69.
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Indications for tonsillectomy and adenoidectomy.扁桃体切除术和腺样体切除术的适应症。
Am Fam Physician. 1971 Mar;3(3):72-8.
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[The treatment of acute recurrent pharyngotonsillitis].[急性复发性咽扁桃体炎的治疗]
Acta Otorhinolaryngol Ital. 2006 Oct;26(5 Suppl 84):5-29.
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Impact of partial and total tonsillectomy on adenoid regrowth.部分扁桃体切除术和全扁桃体切除术对腺样体再生长的影响。
Laryngoscope. 2017 Mar;127(3):753-756. doi: 10.1002/lary.25982. Epub 2016 Apr 14.
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Tonsillectomy and adenoidectomy in the one and two-year-old child.1至2岁儿童的扁桃体切除术和腺样体切除术
Laryngoscope. 1979 Nov;89(11):1764-71. doi: 10.1288/00005537-197911000-00008.
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Tonsillectomy and adenotonsillectomy for recurrent throat infection in moderately affected children.对中度受影响儿童进行扁桃体切除术和腺样体扁桃体切除术以治疗复发性咽喉感染。
Pediatrics. 2002 Jul;110(1 Pt 1):7-15. doi: 10.1542/peds.110.1.7.

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