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与非植入性前置胎盘相比,植入性前置胎盘患者的危险因素及发病率

Risk factors and morbidity in patients with placenta previa accreta compared to placenta previa non-accreta.

作者信息

Zaki Z M, Bahar A M, Ali M E, Albar H A, Gerais M A

机构信息

Department of Obstetrics and Gynecology, Abha Branch College of Medicine, Saudi Arabia.

出版信息

Acta Obstet Gynecol Scand. 1998 Apr;77(4):391-4.

PMID:9598946
Abstract

BACKGROUND

Placenta accreta is associated with high morbidity and most cases occur with placenta previa. This study was carried out in an attempt to define risk factors for placenta accreta in cases of placenta previa and to quantify the increased morbidity of placenta previa accreta in comparison to placenta previa alone.

METHODS

The records of all patients delivered by cesarean section (CS) for placenta previa and accreta during the seven-year period from 1990 to 1996, inclusive, were reviewed. Data regarding the demographic features, previous CS, the incidence of hysterectomy and postpartum morbidity were analyzed.

RESULTS

Out of 23070 deliveries 110 (0.48%) had placenta previa, twelve (0.05%) of whom had placenta previa accreta. There was no significant difference in age and parity. Patients with a history of previous CS showed a significant increase in the incidence of placenta previa accreta (p=0.001). The percentage of accreta increased linearly from 4.1% in patients with no CS to 60% in patients who had had three or more CS. Postpartum hemorrhage and emergency hysterectomy were significantly higher among the previa accreta patients compared with the previa patients alone (p<0.001; p<0.001, respectively).

CONCLUSION

In the presence of a previous history of CS, patients with antepartum diagnosis of placenta previa are considered to be at a greater risk for having placenta accreta. The risk increases with the increase in the number of previous CS. Patients with placenta previa accreta have a significantly higher incidence of PPH and are more likely to undergo emergency hysterectomy.

摘要

背景

胎盘植入与高发病率相关,且大多数病例发生于前置胎盘患者中。本研究旨在确定前置胎盘患者发生胎盘植入的危险因素,并量化与单纯前置胎盘相比,前置胎盘合并胎盘植入时发病率的增加情况。

方法

回顾了1990年至1996年(含)这七年期间因前置胎盘和胎盘植入行剖宫产分娩的所有患者的记录。分析了人口统计学特征、既往剖宫产史、子宫切除率和产后发病率等数据。

结果

在23070例分娩中,110例(0.48%)为前置胎盘,其中12例(0.05%)为前置胎盘合并胎盘植入。年龄和产次无显著差异。有既往剖宫产史的患者发生前置胎盘合并胎盘植入的发生率显著增加(p=0.001)。胎盘植入的比例从无剖宫产史患者中的4.1%线性增加至有三次或更多次剖宫产史患者中的60%。与单纯前置胎盘患者相比,前置胎盘合并胎盘植入患者的产后出血和急诊子宫切除率显著更高(分别为p<0.001;p<0.001)。

结论

对于有既往剖宫产史且产前诊断为前置胎盘的患者,发生胎盘植入的风险更高。风险随着既往剖宫产次数的增加而增加。前置胎盘合并胎盘植入患者的产后出血发生率显著更高,且更有可能接受急诊子宫切除。

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