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初产妇前置胎盘的相关因素及其妊娠结局。

Factors associated with placenta praevia in primigravidas and its pregnancy outcome.

作者信息

Nur Azurah Abdul Ghani, Wan Zainol Zakaria, Lim Pei Shan, Shafiee Mohd Nasir, Kampan Nirmala, Mohsin Wan Syahirah, Mokhtar Norfilza Mohd, Muhammad Yassin Muhammad Abdul Jamil

机构信息

Department of Obstetrics & Gynaecology, UKMMC, Jalan Yaacob Latiff, 56100 Kuala Lumpur, Malaysia.

UKM Molecular Biology Institute, Jalan Yaacob Latiff, 56100 Kuala Lumpur, Malaysia.

出版信息

ScientificWorldJournal. 2014;2014:270120. doi: 10.1155/2014/270120. Epub 2014 Nov 12.

Abstract

AIM

To examine the factors associated with placenta praevia in primigravidas and also compare the pregnancy outcomes between primigravidas and nonprimigravidas.

METHOD

A retrospective cohort study was conducted in women who underwent caesarean section for major placenta praevia in a tertiary university hospital from January 2007 till December 2013. Medical records were reviewed.

RESULT

Among 243 with major placenta praevia, 56 (23.0%) were primigravidas and 187 (77.0%) were nonprimigravidas. Factors associated with placenta praevia in the primigravidas were history of assisted conception (P = 0.02) and history of endometriosis (P = 0.01). For maternal outcomes, the nonprimigravidas required earlier delivery than primigravidas (35.76 ± 2.54 weeks versus 36.52 ± 1.95 weeks, P = 0.03) and had greater blood loss (P = 0.04). A vast majority of the primigravidas had either posterior type II or type III placenta praevia. As for neonatal outcomes, the Apgar score at 1 minute was significantly lower for the nonprimigravidas (7.89 ± 1.72 versus 8.39 ± 1.288.39 ± 1.28, P = 0.02).

CONCLUSION

This study highlighted that endometriosis and assisted conception were highly associated with placenta praevia in primigravida. Understanding the pregnancy outcomes of women with placenta praevia can assist clinicians in identifying patients who are at higher risk of mortality and morbidity. Identifying potential risk factors in primigravida may assist in counseling and management of such patients.

摘要

目的

研究初产妇前置胎盘的相关因素,并比较初产妇与经产妇的妊娠结局。

方法

对2007年1月至2013年12月在某三级大学医院因严重前置胎盘行剖宫产的女性进行回顾性队列研究。查阅病历。

结果

在243例严重前置胎盘患者中,56例(23.0%)为初产妇,187例(77.0%)为经产妇。初产妇前置胎盘的相关因素为辅助受孕史(P = 0.02)和子宫内膜异位症病史(P = 0.01)。对于母体结局,经产妇比初产妇需要更早分娩(35.76 ± 2.54周对36.52 ± 1.95周,P = 0.03),且失血量更多(P = 0.04)。绝大多数初产妇为后壁Ⅱ型或Ⅲ型前置胎盘。至于新生儿结局,经产妇1分钟时的阿氏评分显著低于初产妇(7.89 ± 1.72对8.39 ± 1.28,P = 0.02)。

结论

本研究强调子宫内膜异位症和辅助受孕与初产妇前置胎盘高度相关。了解前置胎盘女性的妊娠结局有助于临床医生识别死亡和发病风险较高的患者。识别初产妇的潜在风险因素可能有助于对此类患者进行咨询和管理。

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本文引用的文献

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Pregnancy outcomes in women with endometriosis.子宫内膜异位症患者的妊娠结局。
Semin Reprod Med. 2013 Mar;31(2):178-82. doi: 10.1055/s-0032-1333484. Epub 2013 Feb 27.
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Maternal morbidity associated with placenta praevia among women who had elective caesarean section.产妇发病率与选择性剖宫产产妇前置胎盘相关。
Eur J Obstet Gynecol Reprod Biol. 2011 Nov;159(1):62-6. doi: 10.1016/j.ejogrb.2011.07.008. Epub 2011 Aug 10.
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Critical analysis of risk factors and outcome of placenta previa.胎盘前置的危险因素及结局的批判性分析。
Arch Gynecol Obstet. 2011 Jul;284(1):47-51. doi: 10.1007/s00404-010-1598-7. Epub 2010 Jul 22.

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