Fernandes R, Fox M, Cotanche D, Lennon K, Kukuruzinska M A
Division of Oral Biology, Boston University Goldman School of Dental Medicine, Massachusetts 02118, USA.
Ann N Y Acad Sci. 1998 Apr 15;842:212-6. doi: 10.1111/j.1749-6632.1998.tb09652.x.
The data presented here provide evidence that the abundance of the ALG7 protein product, GPT, correlates with high proliferative activity during the postnatal development of the hamster SMG development, and that it becomes downregulated with differentiation. Based on our previous studies with yeast, changes in the level of ALG7 expression may be necessary for the events directing salivary cell polarization, migration, differentiation, and apoptosis at distinct developmental stages.
此处呈现的数据表明，ALG7蛋白产物GPT的丰度与仓鼠颌下腺发育出生后阶段的高增殖活性相关，且其随着分化而被下调。基于我们之前对酵母的研究，在不同发育阶段，引导唾液腺细胞极化、迁移、分化和凋亡的过程中，ALG7表达水平的变化可能是必要的。
