Sasoh M, Parel J M, Manns F, Nose I, Comander J, Smiddy W E
Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami School of Medicine, FL 33136, USA.
Ophthalmic Surg Lasers. 1998 May;29(5):410-21.
To quantify and compare holmium:YAG (2.1 microns) and thulium:YAG (2.0 microns) laser-induced scleral shrinkage for retinal buckling procedures.
Two overlapping spots of either laser radiation were applied at the equatorial sclera of 50 human cadaver eyes. Scleral shrinkage was expressed as a relative change of length between two reference points on the scleral surface, and quantified as a function of energy per pulse, total energy, scleral thickness, and intraocular pressure (IOP). Tissue effects were studied histopathologically.
Shrinkage was most dependent on total fluence and attained a maximum of 27% to 30% with an IOP of 4 mm Hg, regardless of scleral thickness or laser parameters, but decreased with increasing IOP. The thulium:YAG laser produced more efficient scleral shrinkage and less collagen damage than the holmium:YAG laser.
The recommended parameters for laser-induced scleral shrinkage are the thulium:YAG laser, with 2.4 J/cm2 per pulse and 12.0 to 14.4 J/cm2 total fluence (5 to 6 pulses). IOP control (< or = 4 mm Hg) is crucial during laser scleral buckling.
对用于视网膜扣带手术的钬:钇铝石榴石(2.1微米)和铥:钇铝石榴石(2.0微米)激光诱导的巩膜收缩进行量化和比较。
在50只人尸体眼的赤道部巩膜上施加两束重叠的激光光斑。巩膜收缩表示为巩膜表面两个参考点之间长度的相对变化,并根据每脉冲能量、总能量、巩膜厚度和眼内压(IOP)进行量化。通过组织病理学研究组织效应。
收缩最依赖于总能量密度,在眼内压为4 mmHg时,无论巩膜厚度或激光参数如何,收缩率最高可达27%至30%,但随眼内压升高而降低。铥:钇铝石榴石激光比钬:钇铝石榴石激光产生更有效的巩膜收缩,且胶原损伤更小。
激光诱导巩膜收缩的推荐参数为铥:钇铝石榴石激光,每脉冲2.4 J/cm²,总能量密度12.0至14.4 J/cm²(5至6个脉冲)。在激光巩膜扣带术中,控制眼内压(≤4 mmHg)至关重要。