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钬:钇铝石榴石和铥:钇铝石榴石激光诱导巩膜收缩用于扣带手术的定量分析。

Quantification of holmium: YAG and thulium: YAG laser-induced scleral shrinkage for buckling procedures.

作者信息

Sasoh M, Parel J M, Manns F, Nose I, Comander J, Smiddy W E

机构信息

Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami School of Medicine, FL 33136, USA.

出版信息

Ophthalmic Surg Lasers. 1998 May;29(5):410-21.

PMID:9599366
Abstract

BACKGROUND AND OBJECTIVE

To quantify and compare holmium:YAG (2.1 microns) and thulium:YAG (2.0 microns) laser-induced scleral shrinkage for retinal buckling procedures.

MATERIALS AND METHODS

Two overlapping spots of either laser radiation were applied at the equatorial sclera of 50 human cadaver eyes. Scleral shrinkage was expressed as a relative change of length between two reference points on the scleral surface, and quantified as a function of energy per pulse, total energy, scleral thickness, and intraocular pressure (IOP). Tissue effects were studied histopathologically.

RESULTS

Shrinkage was most dependent on total fluence and attained a maximum of 27% to 30% with an IOP of 4 mm Hg, regardless of scleral thickness or laser parameters, but decreased with increasing IOP. The thulium:YAG laser produced more efficient scleral shrinkage and less collagen damage than the holmium:YAG laser.

CONCLUSION

The recommended parameters for laser-induced scleral shrinkage are the thulium:YAG laser, with 2.4 J/cm2 per pulse and 12.0 to 14.4 J/cm2 total fluence (5 to 6 pulses). IOP control (< or = 4 mm Hg) is crucial during laser scleral buckling.

摘要

背景与目的

对用于视网膜扣带手术的钬:钇铝石榴石(2.1微米)和铥:钇铝石榴石(2.0微米)激光诱导的巩膜收缩进行量化和比较。

材料与方法

在50只人尸体眼的赤道部巩膜上施加两束重叠的激光光斑。巩膜收缩表示为巩膜表面两个参考点之间长度的相对变化,并根据每脉冲能量、总能量、巩膜厚度和眼内压(IOP)进行量化。通过组织病理学研究组织效应。

结果

收缩最依赖于总能量密度,在眼内压为4 mmHg时,无论巩膜厚度或激光参数如何,收缩率最高可达27%至30%,但随眼内压升高而降低。铥:钇铝石榴石激光比钬:钇铝石榴石激光产生更有效的巩膜收缩,且胶原损伤更小。

结论

激光诱导巩膜收缩的推荐参数为铥:钇铝石榴石激光,每脉冲2.4 J/cm²,总能量密度12.0至14.4 J/cm²(5至6个脉冲)。在激光巩膜扣带术中,控制眼内压(≤4 mmHg)至关重要。

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