Feuerman E J, Alteras I, Bashan D, Lehrer N B
Sabouraudia. 1976 Jul;14(2):217-22.
A new case, the third in Israel, of subcutaneous sporotrichosis is presented. A pigmentary strain of Sporothrix schenckii was cultured from the unopened and necrotic nodules of the left hand and forearm of an 80-year-old male. Experimental inoculation of the isolated fungus into mice led to the dissemination of the organism in the liver, kidneys and lungs inoculated intraperitoneally, and the development of orchitis with abscess formation in those inoculated intratesticularly. In both groups of mice the causative agent was successfully recovered. Three months of treatment with oral potassium iodide led to the disappearance of the lesions. The source of contamination was found to be the soil adhering to fragments of wood. Two strains of a fungus, morphologically identical to the human S. schenckii, were isolated through the mouse procedure and agar-plating method from soil samples collected in the vicinity of the patient's residence. The soil isolates also proved to be pathogenic in animal inoculation. This is the first isolation of S. schenckii from soils in Israel. The possible relationships between the soil isolates and Ceratocystis stenoceras are discussed.
本文报告了以色列的第三例皮下孢子丝菌病新病例。从一名80岁男性左手和前臂未破溃及坏死的结节中培养出申克孢子丝菌的色素沉着菌株。将分离出的真菌实验性接种到小鼠体内，导致该菌在经腹腔接种的小鼠肝脏、肾脏和肺中播散，并在经睾丸内接种的小鼠中引发睾丸炎并形成脓肿。在两组小鼠中均成功分离出病原体。口服碘化钾治疗三个月后病变消失。发现污染源是附着在木片上的土壤。通过小鼠接种程序和琼脂平板法，从患者住所附近采集的土壤样本中分离出两株形态与人申克孢子丝菌相同的真菌。土壤分离株在动物接种中也被证明具有致病性。这是首次在以色列土壤中分离出申克孢子丝菌。文中讨论了土壤分离株与窄孢长喙壳菌之间可能的关系。
