Salvesen R
Neurologisk avdeling, Regionsykehuset i Tromsø.
Tidsskr Nor Laegeforen. 1998 Mar 30;118(9):1410-2.
When young patients suffer a stroke the etiology often differs from that found in the elderly. One of the risk factors for stroke in young people could possibly be migraine. The first author to describe what was probably a migrainous cerebral infarction was Wepfer, in 1727. In recent years, cases of stroke in migraineurs have been frequently reported. Extensive cohort studies and smaller, well-conducted case-control studies seem to confirm that migraine is a risk factor for stroke. However, the risk is only moderately increased, perhaps doubled. Among women under the age of 45, the correlation is greater with a threefold increased risk of stroke in a migraineur; it is even greater in patients suffering attacks of migraine with aura. Pure migrainous infarctions are probably rare and reports are perhaps exaggerated in the literature. Cerebral ischaemia may lead to symptomatic migraine attacks. Overall, the absolute risk of stroke is small enough to validate the opinion that migraine is a benign condition.
年轻患者患中风时，其病因往往与老年人不同。年轻人中风的风险因素之一可能是偏头痛。1727年，韦普费尔首次描述了可能是偏头痛性脑梗死的病例。近年来，偏头痛患者中风的病例屡有报道。广泛的队列研究以及规模较小但开展良好的病例对照研究似乎证实，偏头痛是中风的一个风险因素。然而，风险只是适度增加，可能翻倍。在45岁以下的女性中，偏头痛患者中风风险增加三倍，两者的相关性更大；在患有先兆偏头痛发作的患者中，相关性甚至更大。纯偏头痛性梗死可能很少见，文献中的报道可能有所夸大。脑缺血可能导致有症状的偏头痛发作。总体而言，中风的绝对风险足够小，足以证明偏头痛是一种良性疾病这一观点。
