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[恶性睾丸肿瘤的放射治疗结果]

[Results of radiotherapy of malignant testicular neoplasms].

作者信息

Hackl A, Sager W D

出版信息

Strahlentherapie. 1976 Aug;152(2):103-13.

PMID:960129
Abstract

It is very difficult to compare the therapeutic results of malignant testicular tumours because of the different histological classification systems, the uncertainty in the definition of the different stages, the error rate of the lymphography which amounts up to 35%, and the multitude of surgical, radiation, and chemotherapeutic methods. A histological classification and an exact determination of the stage is required as a condition of beginning a radiotherapy. The desirable focal dose for seminomas is between 4000 and 5000 rad, the maximum dose for teratomas is 6000 rad. For the stages T1-3N0 the iliac and the paraaortic lymph nodes are irradiated, for the stages T1-4N1-2 the interpleural space andthe supraclavicular region are included. For a group of 91 patients there was reached a five-year survival rate of 85,5% in case of seminomas and of 64% in case of teratomas.

摘要

由于存在不同的组织学分类系统、不同分期定义的不确定性、淋巴造影高达35%的错误率以及众多的手术、放疗和化疗方法,很难比较恶性睾丸肿瘤的治疗结果。作为开始放疗的条件,需要进行组织学分类并精确确定分期。精原细胞瘤理想的局部剂量在4000至5000拉德之间,畸胎瘤的最大剂量为6000拉德。对于T1 - 3N0期,照射髂淋巴结和腹主动脉旁淋巴结;对于T1 - 4N1 - 2期,包括胸膜间腔和锁骨上区域。一组91例患者中,精原细胞瘤的五年生存率达到85.5%,畸胎瘤的五年生存率为64%。

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