Kannel W B, Dawber T R, Sorlie P, Wolf P A
Stroke. 1976 Jul-Aug;7(4):327-31. doi: 10.1161/01.str.7.4.327.
From a study of the evolution of atherothrombotic brain infarction (ABI) in the Framingham cohort of 5,209 men and women over 18 years of follow-up, it has been ascertained that hypertensionis the most common and most powerful precursor. Atherothrombotic brain infarction developed in hypertensive patients seven times more often than in normotensive patients, and the risk was proportional to the blood pressure throughout its range.
通过对弗雷明汉队列中5209名18岁以上男性和女性进行超过18年的随访研究动脉粥样硬化性血栓性脑梗死（ABI）的演变情况，已确定高血压是最常见且最有力的先兆因素。高血压患者发生动脉粥样硬化性血栓性脑梗死的几率是血压正常者的7倍，且在整个血压范围内，风险与血压成正比。
