Nebeker A V, Schuytema G S, Griffis W L, Cataldo A
U.S. Environmental Protection Agency, National Health and Ecological Effects Research Laboratory, Western Ecology Division, 200 SW 35th Street, Corvallis, Oregon 97333, USA.
Arch Environ Contam Toxicol. 1998 Jul;35(1):48-51. doi: 10.1007/s002449900347.
The effects of the insecticides Guthion (technical grade) and Guthion 2S (commercial formulation) on survival and growth of tadpoles of the Pacific treefrog Pseudacris regilla, and larvae of the Northwestern salamander Ambystoma gracile and the spotted salamander Ambystoma maculatum were determined in continuous-flow exposures in the laboratory. Ninety-six-hour LC50 values were >3.6 mg/L for P. regilla with technical grade Guthion and 1.47 mg/L with the formulation Guthion 2S (measured as active ingredient Guthion). Ten-day LOAEL and NOAEL values based on length and weight for P. regilla with Guthion were 3.60 and 0.98 mg/L. LOAEL and NOAEL values based on length and weight for P. regilla with Guthion 2S were 0.17 and 0.07 mg/L. The 96-h LC50 for Guthion 2S was 1.67 and 1.90 mg/L for A. gracile and A. maculatum, respectively. LOAEL and NOAEL values based on length and weight for A. gracile with Guthion 2S were 0.22 and 0.10 mg/L; they were 0.11 and 0.03 mg/L for A. maculatum based on weight. These species are as similar in sensitivity as some fish species but are more tolerant to Guthion than most invertebrates.
在实验室的连续流动暴露试验中,测定了杀虫剂谷硫磷(工业级)和谷硫磷2S(商业制剂)对太平洋树蛙(Pseudacris regilla)蝌蚪、细口北螈(Ambystoma gracile)幼体和黄斑蝾螈(Ambystoma maculatum)幼体的存活和生长的影响。对于太平洋树蛙,工业级谷硫磷的96小时半数致死浓度(LC50)值>3.6毫克/升,谷硫磷2S制剂的LC50值为1.47毫克/升(以活性成分谷硫磷计)。基于体长和体重,太平洋树蛙接触谷硫磷的10天最低观察到有害作用水平(LOAEL)和未观察到有害作用水平(NOAEL)分别为3.60毫克/升和0.98毫克/升。基于体长和体重,太平洋树蛙接触谷硫磷2S的LOAEL和NOAEL值分别为0.17毫克/升和0.07毫克/升。谷硫磷2S对细口北螈和黄斑蝾螈的96小时LC50分别为1.67毫克/升和1.90毫克/升。基于体长和体重,细口北螈接触谷硫磷2S的LOAEL和NOAEL值分别为0.22毫克/升和0.10毫克/升;基于体重,黄斑蝾螈的LOAEL和NOAEL值分别为0.11毫克/升和0.