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甲氨蝶呤诱发的幼年类风湿关节炎患儿过敏性肺炎

Methotrexate-induced hypersensitivity pneumonitis in a child with juvenile rheumatoid arthritis.

作者信息

Cron R Q, Sherry D D, Wallace C A

机构信息

Department of Pediatrics, Children's Hospital and Medical Center, Seattle, Washington, USA.

出版信息

J Pediatr. 1998 May;132(5):901-2. doi: 10.1016/s0022-3476(98)70331-2.

DOI:10.1016/s0022-3476(98)70331-2
PMID:9602213
Abstract

Low-dose methotrexate, widely used for juvenile rheumatoid arthritis, has been reported to cause pneumonitis in adults. We report on methotrexate-induced hypersensitivity pneumonitis in a child with juvenile rheumatoid arthritis. Physicians should be aware of this rare complication.

摘要

低剂量甲氨蝶呤广泛用于治疗青少年类风湿性关节炎,据报道可导致成人肺炎。我们报告了1例青少年类风湿性关节炎患儿发生甲氨蝶呤诱发的过敏性肺炎。医生应意识到这种罕见的并发症。

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Methotrexate-induced hypersensitivity pneumonitis in a child with juvenile rheumatoid arthritis.甲氨蝶呤诱发的幼年类风湿关节炎患儿过敏性肺炎
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引用本文的文献

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Folate usage in MTX-treated juvenile idiopathic arthritis (JIA) patients is inconsistent and highly variable.甲氨蝶呤治疗的幼年特发性关节炎(JIA)患者中叶酸的使用情况不一致且差异很大。
Rheumatol Int. 2013 Sep;33(9):2437-40. doi: 10.1007/s00296-013-2696-1. Epub 2013 Feb 12.
2
Treatment of juvenile rheumatoid arthritis.青少年类风湿性关节炎的治疗。
Korean J Pediatr. 2010 Nov;53(11):936-41. doi: 10.3345/kjp.2010.53.11.936. Epub 2010 Nov 30.
3
Recommendations for the use of methotrexate in juvenile idiopathic arthritis.甲氨蝶呤在幼年特发性关节炎中的使用建议。
Paediatr Drugs. 2006;8(6):347-56. doi: 10.2165/00148581-200608060-00003.
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Hypersensitivity pneumonitis in children: clinical features, diagnosis, and treatment.儿童过敏性肺炎:临床特征、诊断与治疗
Paediatr Drugs. 2005;7(4):235-44. doi: 10.2165/00148581-200507040-00003.
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Evidence-based use of methotrexate in children with rheumatic diseases: a consensus statement of the Working Groups Pediatric Rheumatology Germany (AGKJR) and Pediatric Rheumatology Austria.甲氨蝶呤在儿童风湿性疾病中的循证应用:德国儿童风湿病工作组(AGKJR)和奥地利儿童风湿病工作组的共识声明
Rheumatol Int. 2005 Apr;25(3):169-78. doi: 10.1007/s00296-004-0537-y. Epub 2005 Feb 2.
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Paediatr Drugs. 2002;4(5):335-48. doi: 10.2165/00128072-200204050-00006.