Theobald H, Bygren L O, Carstensen J, Hauffman M, Engfeldt P
Department of Clinical Neuroscience and Family Medicine, Karolinska Institute, Stockholm, Sweden.
Int J Epidemiol. 1998 Apr;27(2):194-8. doi: 10.1093/ije/27.2.194.
The aim of this study was to investigate the long-term effects of one general health screening on mortality.
After stratification and randomization of a population of 450,000 inhabitants, two groups were formed, an intervention group of 3064 people and a control group of 29,122 people. From the National Cause of Death Register, data were collected as regards death and causes of deaths for 1970-1990.
Multivariate analysis was used to correct for known confounders. We then found no differences between the groups regarding deaths from all causes, cardiovascular diseases, cancer or accidents and poisoning.
One general health screening seems to have little, if any value in preventing fatal diseases.
本研究的目的是调查一次全面健康筛查对死亡率的长期影响。
在对45万居民进行分层和随机分组后,形成了两组,干预组有3064人,对照组有29122人。从国家死亡原因登记处收集了1970年至1990年期间的死亡及死亡原因数据。
采用多变量分析来校正已知的混杂因素。然后我们发现两组在全因死亡、心血管疾病、癌症或事故及中毒死亡方面没有差异。
一次全面健康筛查在预防致命疾病方面似乎几乎没有价值(如果有价值的话也很小)。