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普通外科和耳鼻喉科手术中困难插管的术前评估:临床多变量风险指数的预测价值

Preoperative assessment for difficult intubation in general and ENT surgery: predictive value of a clinical multivariate risk index.

作者信息

Arné J, Descoins P, Fusciardi J, Ingrand P, Ferrier B, Boudigues D, Ariès J

机构信息

Department of Anaesthesia and Surgical Critical Care, University Hospital of Poitiers, France.

出版信息

Br J Anaesth. 1998 Feb;80(2):140-6. doi: 10.1093/bja/80.2.140.

Abstract

Several clinical multifactorial indexes have been described for predicting difficult laryngoscopy or intubation, or both, mostly in general surgery, and less frequently in ENT surgery. The objective of this study was to develop and validate a single clinical index for prediction of difficulty in tracheal intubation in both ENT and general surgery. We studied a population of 1200 consecutive ENT and general surgical patients. Clinical criteria were tested using univariate and multivariate analysis. Difficult intubation was defined as requiring unusual techniques. Logistic regression identified seven criteria as independent predictors of difficult tracheal intubation; previous history of difficult intubation; pathologies associated with difficult intubation; clinical symptoms of pathological airway; inter-incisor gap and mandible luxation; thyromental distance; head and neck movement; and Mallampati's modified test. Point values were assigned to each of these factors in proportion to regression coefficients representing the relative weight of each predictive intubation difficulty factor, the sum comprising the score. The best predictive threshold was chosen using a receiver operating characteristic curve. We then prospectively studied and validated the score in a population of 1090 consecutive ENT and general surgery patients. The sensitivity and specificity of the predictions were 94% and 96% in general surgery, 90% and 93% in non-cancer ENT surgery, and 92% and 66% in ENT cancer surgery, respectively.

摘要

已经描述了几种临床多因素指标来预测困难喉镜检查或插管,或两者兼而有之,主要用于普通外科,而在耳鼻喉科手术中较少使用。本研究的目的是开发并验证一种单一临床指标,用于预测耳鼻喉科和普通外科气管插管的困难程度。我们研究了连续1200例耳鼻喉科和普通外科患者。使用单因素和多因素分析对临床标准进行了测试。困难插管被定义为需要特殊技术。逻辑回归确定了七个标准作为困难气管插管的独立预测因素:既往困难插管史;与困难插管相关的病理状况;病理性气道的临床症状;门齿间距离和下颌骨脱位;甲颏距离;头颈部活动;以及改良的马兰帕蒂试验。根据代表每个预测插管困难因素相对权重的回归系数,为这些因素中的每一个赋予分值,这些分值之和构成得分。使用受试者工作特征曲线选择最佳预测阈值。然后,我们对连续1090例耳鼻喉科和普通外科患者进行了前瞻性研究并验证了该评分。预测的敏感性和特异性在普通外科分别为94%和96%,在非癌症耳鼻喉科手术中为90%和93%,在耳鼻喉科癌症手术中分别为92%和66%。

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