一名先前未被诊断出感染人类免疫缺陷病毒的患者出现了阴茎部的惰性疱疹性溃疡。

An indolent penile herpetic ulcer in a patient with previously undiagnosed human immunodeficiency virus infection.

作者信息

Tayal S C, Pattman R S, Mclelland J, Sviland L, Snow M H

机构信息

Department of Genito-Urinary Medicine, Newcastle General Hospital, Newcastle Upon Tyne, U.K.

出版信息

Br J Dermatol. 1998 Feb;138(2):334-6. doi: 10.1046/j.1365-2133.1998.02086.x.

DOI:10.1046/j.1365-2133.1998.02086.x

PMID:9602886

Abstract

We report a case of an atypical penile herpetic ulcer in a man with previously undiagnosed human immunodeficiency virus (HIV) infection. Swabs of the lesion were negative for herpes simplex virus (HSV) by culture and electron microscopy. However, histopathology of biopsy material showed characteristic herpetic multinucleate giant cells. Immunochemistry using polyclonal antibodies was positive for HSV1 and HSV2. The lesion completely resolved after treatment with aciclovir and the patient subsequently tested positively for HIV antibodies.

摘要

我们报告一例患有非典型阴茎疱疹性溃疡的男性病例，该男性此前未被诊断出感染人类免疫缺陷病毒（HIV）。病变部位的拭子经培养和电子显微镜检查，单纯疱疹病毒（HSV）呈阴性。然而，活检材料的组织病理学显示有特征性的疱疹多核巨细胞。使用多克隆抗体进行的免疫化学检测显示HSV1和HSV2呈阳性。经阿昔洛韦治疗后病变完全消退，该患者随后HIV抗体检测呈阳性。