Staudinger T, Locker G J, Laczika K, Knapp S, Burgmann H, Wagner A, Weiss K, Zimmerl M, Stoiser B, Frass M
Department of Internal Medicine I, University of Vienna, Austria.
J Trauma. 1998 May;44(5):902-6. doi: 10.1097/00005373-199805000-00026.
To assess the amount of additional information provided by measurements derived from pulmonary artery catheter (PAC) use beyond that derived from clinical evaluation by intensive care residents.
One hundred forty-nine consecutive patients undergoing right-heart catheterization were prospectively included in the study. Before inserting a PAC, physicians had to predict pulmonary arterial pressure (PAP), pulmonary capillary wedge pressure (PCWP), systemic vascular resistance index (SVRI), cardiac index (CI), mixed venous oxygen saturation (SvO2), oxygen delivery (DO2), oxygen consumption (VO2), and pulmonary shunt fraction (Qs/Qt) by selecting a given option on a questionnaire. Ranges of options were chosen to create clear clinical differences among them.
The correct value was predicted in a median of 50% of cases (range, 45-63%). PAP was predicted correctly in 55%, PCWP in 46%, SVRI in 63%, CI in 62%, SvO2 in 45%, DO2 in 45%, VO2 in 51%, and Qs/Qt in 51%. A significant difference was found between estimated and measured values for all parameters (p < 0.01). No significant differences were detected between more and less experienced physicians. There was no significant difference between estimated and measured values with respect to the different courses of intensive care unit admissions or the different indications for PAC insertion.
In a selected group of critically ill patients, the PAC adds valuable and clinically relevant information to clinical assessment in about 50% of cases. Its use should not be withheld in patients with unclear hemodynamic and metabolic profiles.
评估肺动脉导管(PAC)测量所提供的额外信息,超出重症监护住院医师临床评估所获信息的量。
前瞻性纳入149例连续接受右心导管检查的患者。在插入PAC之前,医生必须通过在问卷上选择给定选项来预测肺动脉压(PAP)、肺毛细血管楔压(PCWP)、全身血管阻力指数(SVRI)、心脏指数(CI)、混合静脉血氧饱和度(SvO2)、氧输送(DO2)、氧消耗(VO2)和肺分流分数(Qs/Qt)。选择选项范围以在它们之间产生明显的临床差异。
在中位数为50%的病例中预测出正确值(范围为45%-63%)。PAP预测正确的比例为55%,PCWP为46%,SVRI为63%,CI为62%,SvO2为45%,DO2为45%,VO2为51%,Qs/Qt为51%。所有参数的估计值和测量值之间存在显著差异(p<0.01)。经验丰富和经验较少的医生之间未检测到显著差异。在重症监护病房入院的不同病程或PAC插入的不同指征方面,估计值和测量值之间没有显著差异。
在一组选定的危重症患者中,PAC在约50%的病例中为临床评估增加了有价值且与临床相关的信息。对于血流动力学和代谢情况不明的患者,不应拒绝使用PAC。