Ishimura H, Sata T, Matsumoto T, Takizuka A, Shigematsu A
Department of Anesthesiology, University of Occupational and Environmental Health School of Medicine, Japan, Kitakyushu City.
J Clin Anesth. 1998 May;10(3):228-31. doi: 10.1016/s0952-8180(98)00011-7.
The anesthetic management of a patient with myasthenia gravis (MG) who underwent cardiac surgery with hypothermic cardiopulmonary bypass (CPB) is described. Using total intravenous anesthesia with propofol and a moderate dose fentanyl, the variations of neuromuscular function and serum anti-acetylcholine receptor antibody concentration were examined in relation to hypothermic CPB in the absence of muscle relaxants. The anesthetic technique used may have helped to avoid the risks incidental to muscle relaxants in this patient with MG undergoing hypothermic CPB.
本文描述了一名重症肌无力（MG）患者在低温体外循环（CPB）下进行心脏手术时的麻醉管理。在不使用肌肉松弛剂的情况下，采用丙泊酚和中等剂量芬太尼的全静脉麻醉，研究了低温CPB期间神经肌肉功能和血清抗乙酰胆碱受体抗体浓度的变化。所采用的麻醉技术可能有助于避免该接受低温CPB的MG患者使用肌肉松弛剂带来的风险。
