• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Activation and repression of transcription by differential contact: two sides of a coin.

作者信息

Roy S, Garges S, Adhya S

机构信息

Laboratory of Molecular Biology, NCI, National Institutes of Health, Bethesda, Maryland 20892-4255, USA.

出版信息

J Biol Chem. 1998 Jun 5;273(23):14059-62. doi: 10.1074/jbc.273.23.14059.

DOI:10.1074/jbc.273.23.14059
PMID:9603899
Abstract
摘要

相似文献

1
Activation and repression of transcription by differential contact: two sides of a coin.通过差异接触实现转录的激活与抑制：硬币的两面
J Biol Chem. 1998 Jun 5;273(23):14059-62. doi: 10.1074/jbc.273.23.14059.
2
Transcription regulation by repressosome and by RNA polymerase contact.阻遏物复合体及RNA聚合酶接触介导的转录调控
Cold Spring Harb Symp Quant Biol. 1998;63:1-9. doi: 10.1101/sqb.1998.63.1.
3
Spacing of promoter elements regulates the basal expression of the soxS gene and converts SoxR from a transcriptional activator into a repressor.启动子元件的间距调节soxS基因的基础表达，并将SoxR从转录激活因子转变为阻遏因子。
EMBO J. 1997 Mar 3;16(5):1056-65. doi: 10.1093/emboj/16.5.1056.
4
The effect of the DNA conformation on the rate of NtrC activated transcription of Escherichia coli RNA polymerase.sigma(54) holoenzyme.DNA构象对大肠杆菌RNA聚合酶σ⁵⁴全酶NtrC激活转录速率的影响。
J Mol Biol. 2000 Jul 21;300(4):709-25. doi: 10.1006/jmbi.2000.3921.
5
TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter.转录。通过核心启动子整体拓扑结构的变化进行变构转录调控。
Science. 2015 Aug 21;349(6250):877-81. doi: 10.1126/science.aaa9809.
6
Transcription activation and repression by interaction of a regulator with the alpha subunit of RNA polymerase: the model of phage phi 29 protein p4.通过调节因子与RNA聚合酶α亚基的相互作用实现转录激活和抑制：噬菌体φ29蛋白p4的模型
Prog Nucleic Acid Res Mol Biol. 1998;60:29-46. doi: 10.1016/s0079-6603(08)60888-0.
7
Regulation of gene expression in Vibrio cholerae by ToxT involves both antirepression and RNA polymerase stimulation.霍乱弧菌中ToxT对基因表达的调控涉及抗阻遏和RNA聚合酶刺激。
Mol Microbiol. 2002 Jan;43(1):119-34. doi: 10.1046/j.1365-2958.2002.02721.x.
8
Purification and in vitro activities of the Bacillus subtilis TnrA transcription factor.枯草芽孢杆菌TnrA转录因子的纯化及体外活性
J Mol Biol. 2000 Jun 30;300(1):29-40. doi: 10.1006/jmbi.2000.3846.
9
Physical and functional interaction of the archaeal single-stranded DNA-binding protein SSB with RNA polymerase.古菌单链DNA结合蛋白SSB与RNA聚合酶的物理和功能相互作用。
Nucleic Acids Res. 2004 Feb 10;32(3):1065-74. doi: 10.1093/nar/gkh259. Print 2004.
10
Repression of transcription initiation at 434 P(R) by 434 repressor: effects on transition of a closed to an open promoter complex.434阻遏蛋白对434 P(R)转录起始的抑制作用：对封闭型启动子复合物向开放型启动子复合物转变的影响。
J Mol Biol. 2001 Jun 8;309(3):573-87. doi: 10.1006/jmbi.2001.4702.

引用本文的文献

1
A systematic survey of TF function in E. coli suggests RNAP stabilization is a prevalent strategy for both repressors and activators.一项对大肠杆菌中TF功能的系统调查表明，RNA聚合酶稳定化是阻遏物和激活物的普遍策略。
Nucleic Acids Res. 2025 Feb 8;53(4). doi: 10.1093/nar/gkaf058.
2
Predicting bacterial promoter function and evolution from random sequences.从随机序列预测细菌启动子功能和进化。
Elife. 2022 Jan 26;11:e64543. doi: 10.7554/eLife.64543.
3
Quantifying the regulatory role of individual transcription factors in Escherichia coli.
量化单个转录因子在大肠杆菌中的调控作用。
Cell Rep. 2021 Nov 9;37(6):109952. doi: 10.1016/j.celrep.2021.109952.
4
The Context-Dependent Influence of Promoter Sequence Motifs on Transcription Initiation Kinetics and Regulation.启动子序列基序对转录起始动力学和调控的上下文依赖性影响。
J Bacteriol. 2021 Mar 23;203(8). doi: 10.1128/JB.00512-20.
5
How the avidity of polymerase binding to the -35/-10 promoter sites affects gene expression.聚合酶与-35/-10 启动子位点的亲和力如何影响基因表达。
Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13340-13345. doi: 10.1073/pnas.1905615116. Epub 2019 Jun 13.
6
Measuring cis-regulatory energetics in living cells using allelic manifolds.利用等位基因流形测量活细胞中的顺式调控能量学。
Elife. 2018 Dec 20;7:e40618. doi: 10.7554/eLife.40618.
7
Bacterial RNA Polymerase-DNA Interaction-The Driving Force of Gene Expression and the Target for Drug Action.细菌RNA聚合酶与DNA的相互作用——基因表达的驱动力及药物作用靶点
Front Mol Biosci. 2016 Nov 9;3:73. doi: 10.3389/fmolb.2016.00073. eCollection 2016.
8
Structural basis of transcription activation.转录激活的结构基础。
Science. 2016 Jun 10;352(6291):1330-3. doi: 10.1126/science.aaf4417.
9
CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.CarD利用小沟楔形机制来稳定RNA聚合酶开放启动子复合物。
Elife. 2015 Sep 8;4:e08505. doi: 10.7554/eLife.08505.
10
Different Modes of Transactivation of Bacteriophage Mu Late Promoters by Transcription Factor C.转录因子C对噬菌体Mu晚期启动子的不同反式激活模式
PLoS One. 2015 Jun 9;10(6):e0129504. doi: 10.1371/journal.pone.0129504. eCollection 2015.