噪声诱导毛细胞损失的电化学机制研究：氨基氧乙酸（AOAA）噪声实验
An examination of an electrochemical mechanism for noise-induced hair cell loss: noise with amino-oxyacetic acid (AOAA).
作者信息
Bobbin R P, Guth M S, Mines A B
出版信息
Trans Sect Otolaryngol Am Acad Ophthalmol Otolaryngol. 1976 May-Jun;82(3 Pt 1):299-304.
PMID:960397
Abstract
Pretreatment of guinea pigs with AOAA was found to reduce the incidence of hair cell loss due to noise exposure. Since AOAA reduces the endocochlear potential, we propose an electrochemical model as an extension of the Davis model to explain the protective effect of AOAA.
摘要
研究发现，用氨基氧乙酸（AOAA）预处理豚鼠可降低因噪声暴露导致的毛细胞损失发生率。由于AOAA会降低内淋巴电位，我们提出一个电化学模型作为戴维斯模型的扩展，以解释AOAA的保护作用。
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