原位肝移植术后接受他克莫司（FK506）治疗的儿童出现明显左心室肥厚。
Marked left ventricular hypertrophy in children on tacrolimus (FK506) after orthotopic liver transplantation.
作者信息
Chang R K, Alzona M, Alejos J, Jue K, McDiarmid S V
机构信息
Department of Pediatrics, UCLA Medical Center, Los Angeles, California 90024, USA.
出版信息
Am J Cardiol. 1998 May 15;81(10):1277-80. doi: 10.1016/s0002-9149(98)00126-x.
PMID:9604971
Abstract
Although the cardiac effects of tacrolimus (FK506) have not been well documented, clinical cases of children on FK506 who developed hypertrophic obstructive cardiomyopathy have been reported. We report 2 cases of marked concentric hypertrophy of the left ventricular myocardium found at autospy in children on FK506.
摘要
尽管他克莫司（FK506）对心脏的影响尚未有充分记录，但已有报告称使用FK506的儿童出现肥厚性梗阻性心肌病的临床病例。我们报告了2例在尸检中发现使用FK506的儿童左心室心肌出现明显同心性肥厚的病例。
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