Chang R K, Alzona M, Alejos J, Jue K, McDiarmid S V
Department of Pediatrics, UCLA Medical Center, Los Angeles, California 90024, USA.
Am J Cardiol. 1998 May 15;81(10):1277-80. doi: 10.1016/s0002-9149(98)00126-x.
Although the cardiac effects of tacrolimus (FK506) have not been well documented, clinical cases of children on FK506 who developed hypertrophic obstructive cardiomyopathy have been reported. We report 2 cases of marked concentric hypertrophy of the left ventricular myocardium found at autospy in children on FK506.
尽管他克莫司（FK506）对心脏的影响尚未有充分记录，但已有报告称使用FK506的儿童出现肥厚性梗阻性心肌病的临床病例。我们报告了2例在尸检中发现使用FK506的儿童左心室心肌出现明显同心性肥厚的病例。
