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[Structural and functional organization of sexual dimorphism zones of the amygdala in the normal state and in alloxan diabetes].

作者信息

Akhmadeev A V, Nagaeva D V, Kalimullina L B, Kaiumov F A

机构信息

Department of Histology, Bashkirian State Medical University, Ufa.

出版信息

Morfologiia. 1998;113(1):68-72.

PMID:9606667
Abstract

Cytoarchitectonics and neuronal organization of sexual dimorphism zones (ZSD) of amygdala, one of the brain higher neuroendocrine centres were studied and reactive changes of this zone neurons were analysed in rats with chronic alloxan diabetes that modulate type I diabetes mellitus in man. Structural organization of main ZSD of amygdala--dorsomedial, anterior and basolateral nuclei displays its characteristic topographical and cytoarchitectonic peculiarities. Neuronal organisation of main amygdala zones is characterized by different ratio of intensely and sparsely dendritic long-axonal neurons. Neurons of all ZSD respond to insulin deficiency--induced disturbances of carbohydrate metabolism in the same type. Reactive changes of neurons defined consist in chromatophilia development and neuron shrinkage and also in significant decline in cell nuclear volume.

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