[多肽生长因子和激素在交感肾上腺细胞系神经介质状态形成中的作用]
[The role of polypeptide growth factors and hormones in the formation of neuromediator status of a sympathoadrenal cell line].
作者信息
Kaliunov V N, Buravskiĭ V A, Gronskaia R I, Polukoshko E F
机构信息
Laboratory of Regulatory Protein and Peptides, Byelorussian Academy of Sciences, Minsk.
出版信息
Morfologiia. 1998;113(1):77-81.
Formation of the mixed pattern of neurotransmitter synthesis at intermediate stage of neuron functional differentiation involving interaction of nerve and epidermal growth factors (NGF and EGF) and also thyroxine was analysed histochemically. Analysis of change dynamics of acetyl cholinesterase catecholamine ratio influenced by NGF demonstrated its dependence on the cell type. Thyroxine potentiates NGF effect while EGF stimulates NGF-induced ACE increase only during the initial period.
对神经元功能分化中期神经递质合成混合模式的形成进行了组织化学分析，该过程涉及神经生长因子（NGF）、表皮生长因子（EGF）以及甲状腺素的相互作用。对受NGF影响的乙酰胆碱酯酶与儿茶酚胺比例变化动态的分析表明，其依赖于细胞类型。甲状腺素增强NGF的作用，而EGF仅在初期刺激NGF诱导的乙酰胆碱酯酶增加。
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