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[二期莱姆病神经螺旋体病的胸腹表现]

[Thoraco-abdominal manifestation of stage II Lyme neuroborreliosis].

作者信息

Pfadenhauer K, Schönsteiner T, Stöhr M

机构信息

Neurologische Klinik mit klinischer Neurophysiologie, Zentralklinikum Augsburg.

出版信息

Nervenarzt. 1998 Apr;69(4):296-9. doi: 10.1007/s001150050273.

DOI:10.1007/s001150050273
PMID:9606679
Abstract

In the past little attention was paid to the thoracoabdominal manifestation of Lyme radiculoneuritis, because paralysis of the abdominal wall muscles was considered to be a very uncommon clinical manifestation of Lyme neuroborreliosis. In a group of 90 patients suffering from early stage Lyme neuroborreliosis we found abdominal wall weakness in 11 cases. In the majority of patients thoracoabdominal radiculoneuritis was located in the lower thoracic segments (Th 7-12) and involved more than 3 segments (62%) mostly bilaterally (69%). Abdominal wall paralysis was mostly bilateral (91%) and involved always the lower half of the abdominal wall. It was very severe in 18%. Electromyographic studies were done in the paraspinal and abdominal wall muscles showing fibrillation potentials and positive sharp waves in 86% and 50%, respectively. Diagnosis of thoracoabdominal radiculoneuritis in Lyme neuroborreliosis may be difficult and diagnostic errors may occur. Therefore we recommend to look carefully for paralysis of the abdominal wall, which can easily be overlooked on routine neurological examination. In patients from an area with a high incidence of Lyme disease it is recommended to exclude neuroborreliosis even in patients with known diabetes mellitus in order to avoid the misdiagnosis of diabetic thoracoabdominal radiculopathy. This has occured in 2 of our patients.

摘要

过去,人们很少关注莱姆神经根神经炎的胸腹表现,因为腹壁肌肉麻痹被认为是莱姆神经疏螺旋体病非常罕见的临床表现。在一组90例早期莱姆神经疏螺旋体病患者中,我们发现11例存在腹壁无力。大多数患者的胸腹神经根神经炎位于胸下段(Th 7 - 12),累及超过3个节段(62%),大多为双侧受累(69%)。腹壁麻痹大多为双侧性(91%),且总是累及腹壁下半部。18%的患者病情非常严重。对椎旁肌和腹壁肌肉进行了肌电图研究,结果分别显示86%和50%的患者有纤颤电位和正锐波。莱姆神经疏螺旋体病中胸腹神经根神经炎的诊断可能困难,且可能出现诊断错误。因此,我们建议仔细检查腹壁麻痹情况,这在常规神经系统检查中很容易被忽视。对于来自莱姆病高发地区的患者,即使是已知患有糖尿病的患者,也建议排除神经疏螺旋体病,以避免误诊为糖尿病性胸腹神经根病。我们的2例患者就出现了这种情况。

相似文献

1
[Thoraco-abdominal manifestation of stage II Lyme neuroborreliosis].[二期莱姆病神经螺旋体病的胸腹表现]
Nervenarzt. 1998 Apr;69(4):296-9. doi: 10.1007/s001150050273.
2
Lyme polyradiculoneuropathy presenting as increasing abdominal girth.表现为腹围增大的莱姆病性多神经根神经病
Neurology. 1990 Feb;40(2):373-5. doi: 10.1212/wnl.40.2.373.
3
Polymerase chain reaction in diagnosis of Borrelia burgdorferi infections and studies on taxonomic classification.聚合酶链反应在伯氏疏螺旋体感染诊断及分类学研究中的应用
APMIS Suppl. 2002(105):1-40.
4
Neurological findings of Lyme disease.莱姆病的神经学表现。
Yale J Biol Med. 1984 Jul-Aug;57(4):481-3.
5
[Inflammatory demyelinating neuropathy in neuroborreliosis].[神经莱姆病中的炎性脱髓鞘性神经病]
Wien Med Wochenschr. 1995;145(7-8):188-90.
6
[Chronic neuroborreliosis in Lyme disease].
Ter Arkh. 1996;68(5):41-4.
7
Ticking off diagnoses of abdominal pain: early neuroborreliosis with radiculopathy.罗列腹痛的诊断结果:伴有神经根病的早期神经莱姆病。
Neth J Med. 2018 Sep;76(7):336-338.
8
[Facial diplegia as the presenting feature of Lyme disease].[面神经麻痹作为莱姆病的首发症状]
Rev Med Interne. 2015 May;36(5):352-5. doi: 10.1016/j.revmed.2014.05.002. Epub 2014 Aug 2.
9
[Paralysis of abdominal muscles caused by Lyme disease].[莱姆病导致的腹部肌肉麻痹]
Rev Neurol (Paris). 1993;149(12):810-2.
10
An Enzyme-Linked Immunosorbent Spot Assay Measuring Borrelia burgdorferi B31-Specific Interferon Gamma-Secreting T Cells Cannot Discriminate Active Lyme Neuroborreliosis from Past Lyme Borreliosis: a Prospective Study in the Netherlands.酶联免疫斑点法检测伯氏疏螺旋体 B31 特异性干扰素 γ 分泌 T 细胞不能区分活动性莱姆神经Borreliosis 与既往莱姆 Borreliosis:荷兰的一项前瞻性研究。
J Clin Microbiol. 2018 Mar 26;56(4). doi: 10.1128/JCM.01695-17. Print 2018 Apr.

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Severe orthostatic hypotension in a diabetic patient may not be due to diabetic autonomic neuropathy.糖尿病患者严重的直立性低血压可能不是由于糖尿病自主神经病变引起的。
Clin Med (Lond). 2011 Jun;11(3):290-1. doi: 10.7861/clinmedicine.11-3-290.