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[I型胃异位胰腺中朗格汉斯胰岛的功能特征]

[Functional characteristics of the Langerhans islets in type I gastric heterotopic pancreas].

作者信息

Gualco Neves G, Angujar Blanco R, Ortega Ortuzar V, Pizzarossa C

机构信息

Departamento de Anatomía Patológica, Hospital de Clínicas, Facultad de Medicina, Montevideo, Uruguay.

出版信息

Acta Gastroenterol Latinoam. 1998;28(1):23-5.

PMID:9607070
Abstract

In a retrospective five years study of gastric wall tumors, we selected the type 1 heterotopic pancreas. The assessment of fibrosis and inflammatory infiltrate were performed. Also the immunohistochemical evaluation with monoclonal antibodies for insulin, glucagon, p substance, somatostatin, gastrin and antichimotrypsin. None of the case showed remarkable fibrosis or inflammatory infiltrate. All the Langerhans's islets stained positive for 2 or 3 hormones, gastrin and antichimotrypsin were always negative. These findings are comparable with others previously reported, but no cases of evaluation of islet's gastrin exist in the literature reviewed.

摘要

在一项对胃壁肿瘤的回顾性五年研究中,我们选取了1型异位胰腺。进行了纤维化和炎性浸润的评估。还使用胰岛素、胰高血糖素、P物质、生长抑素、胃泌素和抗胰凝乳蛋白酶的单克隆抗体进行了免疫组化评估。所有病例均未显示出明显的纤维化或炎性浸润。所有胰岛对2种或3种激素染色呈阳性,胃泌素和抗胰凝乳蛋白酶始终为阴性。这些发现与先前报道的其他研究结果相当,但在所查阅的文献中不存在对胰岛胃泌素进行评估的病例。

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