Kontsek P, Kontseková E
Institute of Virology, Slovak Academy of Sciences, Bratislava, Slovak Republic.
Acta Virol. 1997 Dec;41(6):349-53.
The nature and mode of action of interferon (IFN) have been intensively studied for more than 40 years. In this review, we summarize the current knowledge of IFN putting emphasize on transitions in its definition, understanding of its physiological role and nomenclature, and on brief characterization of individual IFN families. Finally, the evolution of IFN and relations between the IFN families are discussed.
干扰素(IFN)的性质和作用方式已被深入研究了40多年。在这篇综述中,我们总结了关于干扰素的现有知识,重点强调了其定义的转变、对其生理作用和命名的理解,以及对各个干扰素家族的简要特征描述。最后,讨论了干扰素的进化以及干扰素家族之间的关系。