Chan K L, Tam P K
Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
J Pediatr Surg. 1998 May;33(5):783-6. doi: 10.1016/s0022-3468(98)90221-4.
This is the first report of the successful use of percutaneous transcatheter arterial embolization (TAE) in controlling hemorrhage from ruptured hepatoblastoma, allowing early major hepatic resection to be performed safely in a young infant. A 6-month-old girl presented with a huge abdominal mass and was found to have a hepatoblastoma that measured 15 x 10 x 12 cm and arose from the right lobe of her liver on computed tomography (CT) scan examination. The tumor spontaneously ruptured, and she went into shock. TAE with gelfoam cube particles successfully arrested the tumor bleeding and allowed stabilization of her blood pressure with blood transfusion. Right trisegmentectomy was performed 12 hours later. The postoperative course was uneventful. With three courses of cisplatin, vincristine, and 5-fluorouracil after the hepatectomy, the serum alpha-fetoprotein level returned to normal, and the patient has remained well 4 months postoperation.
这是关于经皮经导管动脉栓塞术(TAE)成功用于控制破裂肝母细胞瘤出血的首例报告,使得在一名幼儿中能够安全地早期进行大范围肝切除术。一名6个月大的女孩因巨大腹部肿块就诊,计算机断层扫描(CT)检查发现其患有肝母细胞瘤,大小为15×10×12 cm,起源于肝脏右叶。肿瘤自发破裂,她陷入休克。用明胶海绵方块颗粒进行TAE成功止住了肿瘤出血,并通过输血使她的血压稳定。12小时后进行了右三叶切除术。术后过程顺利。肝切除术后接受了三个疗程的顺铂、长春新碱和5-氟尿嘧啶治疗,血清甲胎蛋白水平恢复正常,患者术后4个月情况良好。