Studlar M, Pichler O
Z Ernahrungswiss. 1976 Mar;15(1):80-91. doi: 10.1007/BF02283141.
Peroral application of caffeine or theophylline causes a significant increase of the free fatty acids and the free glycerol of the serum; blood sugar and cholesterol are not influenced. FFA and free glycerol decrease during the day by food intake, blood sugar and triglycerides rise. The ingestion of coffee (1-3 cups) does not influence fat and carbohydrate metabolism. To induce a significant increase of lipolysis and of serum triglyceride levels high caffeine doses (1000 mg) are required. Summarizing the data presented, the authors conclude that coffee intake (at dosages compatible with normal nutrition) does not deteriorate glucose tolerance and does not interfere with the fat metabolism. Our findings are confirmed by epidemiologic investigations which have shown that coffee intake is no risk factor for myocardial infarction.
经口给予咖啡因或茶碱会导致血清中游离脂肪酸和游离甘油显著增加；血糖和胆固醇不受影响。白天，通过食物摄入，游离脂肪酸（FFA）和游离甘油会减少，而血糖和甘油三酯会升高。饮用咖啡（1 - 3杯）不会影响脂肪和碳水化合物的代谢。要显著增加脂肪分解和血清甘油三酯水平，需要高剂量的咖啡因（1000毫克）。总结所呈现的数据，作者得出结论，摄入咖啡（在与正常营养相符的剂量下）不会损害葡萄糖耐量，也不会干扰脂肪代谢。我们的研究结果得到了流行病学调查的证实，这些调查表明摄入咖啡不是心肌梗死的危险因素。
