[分泌型免疫球蛋白A的比较研究]
[Comparative study of secretory IgA].
作者信息
Rico Méndez F G, Massey L F, Rendón L, Múgica J J, Alvarez L
机构信息
Unidad de Investigación e Información de Enfermedades Respiratorias, Hospital General, CMN La Raza, IMSS, México.
出版信息
Rev Alerg Mex. 1998 Jan-Feb;45(1):13-5.
OBJECTIVE
The aim of this study was measure and compare Secretory IgA levels in the respiratory tract.
DESIGN
Cross-sectional study.
SETTING
Neumology Department of General Hospital. La Raza Medical Center Mexico.
MATERIAL AND METHOD
There were 35 volunteers. Samples of sputum, washings nasopharyngeal and bronchial was obtained from thirty five patients with COPD. Measurement of SIgA levels was performed by nephelometric technique. Results is reported as ratio of SIgA concentration/Total proteins concentration named SIgA relative concentration. Correlation index was obtained of three type of samples.
RESULTS
The SIgA values of sputum, washings nasopharyngeal and bronchial was similar similar +/- 0.011, 0.064 +/- 0.007 and 0.082 +/- 0.017 respectively). Multiple correlation was r = 0.508 (p < 0.01).
目的
本研究的目的是测量和比较呼吸道中的分泌型IgA水平。
设计
横断面研究。
地点
墨西哥拉扎医疗中心综合医院肺病科。
材料与方法
有35名志愿者。从35例慢性阻塞性肺疾病（COPD）患者中获取痰液、鼻咽冲洗液和支气管冲洗液样本。采用比浊法测量分泌型IgA水平。结果以分泌型IgA浓度/总蛋白浓度的比值表示，称为分泌型IgA相对浓度。获得了三种样本类型的相关指数。
结果
痰液、鼻咽冲洗液和支气管冲洗液的分泌型IgA值相似（分别为0.011±0.011、0.064±0.007和0.082±0.017）。多重相关性r = 0.508（p < 0.01）。
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