[Studies on the specificity of alanine aminopeptidase and its variants in the serum in hepatobiliary diseases].

After examinations on a mixed number of patients (236 patients) the increases of the activities of the alanine aminopeptidase in the serum with relatively high certainty may be traced back to diseases of the liver and of the bile ducts. The hepatobiliary specifity is disturbed only by generalised dermatological diseases, especially eczemas. Changes in the electrophoretic pattern of the serum alanine aminopeptidase are also relatively specific for diseases or lesions of the hepatobiliary system. In 11 of the 12 anomalous zymograms of the alanine aminopeptidase observed among 236 patients the aimed search resulted in an alteration of the hepatobiliary system.