Rieche K
Z Gesamte Inn Med. 1976 Apr 15;31(8):217-21.
In haemoblastoses the chemotherapy is able to achieve remissions and prolongations of the survival time. The combined or polychemotherapy, respectively, is here comparatively more effective than the monotherapy. In haemoblastoses the concept of the maximal destruction of tumours (induction therapy) could be realised by means of consolidation and maintenance therapy. The prediction of the therapy effects by inclusion of different host parameters (morphology, immune state, age, sensibility test) may only approximately be done. In the induction and maintenance of the remission the supportive therapeutic measures play an essential role. By the development of selective cytostatic drugs and further utilisation of the results of molecular-biological experiments further ameliorations of the therapeutic situation are to be awaited.
在血液病中，化疗能够实现缓解并延长生存时间。联合化疗或多药化疗在此相对单药化疗更有效。在血液病中，通过巩固和维持治疗可以实现肿瘤最大程度破坏（诱导治疗）的概念。纳入不同宿主参数（形态学、免疫状态、年龄、敏感性试验）来预测治疗效果只能大致进行。在缓解的诱导和维持过程中，支持性治疗措施起着至关重要的作用。随着选择性细胞毒性药物的发展以及分子生物学实验结果的进一步应用，有望进一步改善治疗状况。
