Wienbeck M
Z Gastroenterol. 1976 Mar;14 Suppl:138-47.
The work-up of patients with benign diseases of the esophagus should start with a diagnostic evaluation. This includes a carefully taken history, radiologic and endoscopic examinations and, in suspected reflux disease, recording of intraesophageal pH. For the evaluation of functional troubles esophageal manometry is recommended. Patients with complicated reflux disease and failures of antireflux treatment should be operated upon. In high peptic stenoses, Barrett's syndrome should be carefully looked for. Achalasia is treated by pneumatic dilatations with more than 90% good or satisfactory results. But diffuse esophageal spasm is little responsive to therapy. There is a risk of secondary carcinoma in Barrett's syndrome, achalasia, caustic lesions and Plummer-Vinson syndrome. Therefore these patients should be seen at regular intervals. There is an urgent need for controlled studies evaluating the comparative results of medical and surgical therapy.
对患有食管良性疾病的患者进行检查时,应从诊断评估开始。这包括详细的病史采集、放射学和内镜检查,对于疑似反流性疾病的患者,还需记录食管内pH值。为评估功能性问题,建议进行食管测压。患有复杂性反流性疾病且抗反流治疗失败的患者应接受手术治疗。对于高度消化性狭窄患者,应仔细检查是否存在巴雷特综合征。贲门失弛缓症通过气囊扩张治疗,90%以上效果良好或令人满意。但弥漫性食管痉挛对治疗反应不佳。巴雷特综合征、贲门失弛缓症、腐蚀性损伤和普卢默-文森综合征患者有继发癌的风险。因此,这些患者应定期复诊。迫切需要进行对照研究,以评估药物治疗和手术治疗的对比结果。