Feurle G E
Z Gastroenterol. 1976 Mar;14 Suppl:95-8.
A pathophysiological role of gastrin has been established only in the Zollinger-Ellison-Syndrome. Hypergastrinemia may be found in cases with prenicious anemia, atrophic gastritis and after all forms of vagotomy; furthermore in the excluded antrum syndrome, the short bowel syndrome, in renal insufficiency, pyloric stenoses and after oral or parenteral administration of calcium. The role of gastrin in the pathogenesis of duodenal ulcer is unknown.
胃泌素的病理生理作用仅在卓-艾综合征中得到证实。高胃泌素血症可见于恶性贫血、萎缩性胃炎患者以及接受各种形式迷走神经切断术后的患者;此外,在胃窦排除综合征、短肠综合征、肾功能不全、幽门狭窄患者以及口服或静脉注射钙后也可出现。胃泌素在十二指肠溃疡发病机制中的作用尚不清楚。