Saygili U, Uslu T, Erten O, Doğan E
Dokuz Eylül University, Faculty of Medicine, Department of Obstetrics and Gynecology, Izmir, Turkey.
Eur J Gynaecol Oncol. 1998;19(2):182-5.
Twenty-one borderline ovarian tumour cases, diagnosed and treated in our oncology section between 1986 and 1996, were retrospectively analysed. Thirty-three percent of the cases had serous tumours and the rest (66.6%) were mucinous, 57.1% of the mucinous tumours were the intestinal type and the remaining 42.9% were the endocervical type. When all the cases were analysed, the average age was 45.4+/-18.6 years, the average follow-up period was 5.5+/-2.6 years. The preoperative average CA125 level was 55.1+/-51.9 U/mL, and for CA19.9 it was 48.2+/-47.8 U/mL. Of the patients 85.7% were stage I and 14.3% state III. There were not any significant differences between the serous, intestinal-type mucinous and endometroid-type mucinous tumours regarding tumour volumes (p>0.05). When serous and mucinous tumours were compared according to the tumour markers, CA125 levels were significantly higher in the serous tumours (p=0.04) and CA19.9 levels were significantly higher in the mucinous tumours (p=0.02). All of the patients are under our follow-up and are in remission, except one, who died in the third year of the treatment because of chronic renal failure unrelated to the ovarian pathology.
对1986年至1996年间在我们肿瘤科诊断和治疗的21例卵巢交界性肿瘤病例进行了回顾性分析。33%的病例为浆液性肿瘤,其余(66.6%)为黏液性肿瘤,57.1%的黏液性肿瘤为肠型,其余42.9%为宫颈内膜型。对所有病例进行分析时,平均年龄为45.4±18.6岁,平均随访期为5.5±2.6年。术前平均CA125水平为55.1±51.9 U/mL,CA19.9为48.2±47.8 U/mL。85.7%的患者为I期,14.3%为III期。浆液性、肠型黏液性和子宫内膜样黏液性肿瘤在肿瘤体积方面无显著差异(p>0.05)。根据肿瘤标志物比较浆液性和黏液性肿瘤时,浆液性肿瘤的CA125水平显著更高(p=0.04),黏液性肿瘤的CA19.9水平显著更高(p=0.02)。除1例在治疗第三年因与卵巢病变无关的慢性肾衰竭死亡外,所有患者均在我们的随访中且病情缓解。