Dembélé T, Votava M, Obdrzálek V
Mikrobiologický ústav, Lékarská fakulta Masarykovy univerzity a Fakultní nemocnice u sv. Anny, Bron.
Epidemiol Mikrobiol Imunol. 1998 Apr;47(2):43-6.
The antagonistic action of lactobacilli is an important factor in the protection of the vagina of fertile women from infection by other microorganisms. In the present study the authors investigated 17 strains of lactobacilli, incl. 11 of vaginal origin. The objective was to investigate in more detail the antibacterial activity of lactobacilli and to attempt to assess substances responsible for inhibition. The investigated lactobacilli inhibited some strains of Escherichia coli, Serratia marcescens, Shigella boydii, Staphylococcus aureus, Listeria monocytogenes, Listeria innocua and Listeria ivanovii with different intensity. The authors provided evidence that inhibition is due mainly to organic acids and to a lesser extent to bacteriocins. The authors assessed also the effect of enterobacteria on lactobacilli but did not observe any inhibition of lactobacilli.
乳酸杆菌的拮抗作用是保护育龄妇女阴道免受其他微生物感染的一个重要因素。在本研究中,作者调查了17株乳酸杆菌,其中包括11株源自阴道的菌株。目的是更详细地研究乳酸杆菌的抗菌活性,并试图评估负责抑制作用的物质。所研究的乳酸杆菌以不同强度抑制了一些大肠杆菌、粘质沙雷氏菌、鲍氏志贺氏菌、金黄色葡萄球菌、单核细胞增生李斯特菌、无害李斯特菌和伊氏李斯特菌菌株。作者提供的证据表明,抑制作用主要归因于有机酸,其次才是细菌素。作者还评估了肠杆菌对乳酸杆菌的影响,但未观察到对乳酸杆菌的任何抑制作用。