Plans-Rubió P
General Direction of Public Health, Barcelona.
Int J Technol Assess Health Care. 1998 Spring;14(2):320-30. doi: 10.1017/s0266462300012289.
Individual programs for prevention of cardiovascular disease include dietary and drug treatment of hypercholesterolemia, hypertension treatment, and smoking cessation therapies. In this study, the cost-effectiveness of available cardiovascular prevention programs was assessed in Spain in terms of net cost per life-year gained (LYG). Cost-effectiveness ratios ranged from US $2,600 to $80,000 per LYG in men and from $4,500 to $230,000 per LYG in women. In men aged 40-59 years, the ranking of increasing cost-effectiveness was: smoking cessation ($2,608-3,738 per LYG); treatment of moderate and severe hypertension ($8,564-38,678 per LYG); treatment of mild hypertension ($11,906-59,840 per LYG); dietary treatment ($16,143-20,158 per LYG); and drug treatment of hypercholesterolemia ($33,850-81,010 per LYG). In women, the ranking list was:smoking cessation ($4,482-5,756 per LYG), treatment of moderate and severe hypertension ($9,585-57,983 per LYG), treatment of mild hypertension ($15,248-86,075 per LYG), dietary treatment ($57,175-62,154 per LYG); and drug treatment of hypercholesterolemia ($104,100-259,150 per LYG).
心血管疾病的个体预防方案包括高胆固醇血症的饮食和药物治疗、高血压治疗以及戒烟疗法。在本研究中，在西班牙根据每获得一个生命年（LYG）的净成本评估了现有心血管预防方案的成本效益。男性的成本效益比为每LYG 2600美元至80000美元，女性为每LYG 4500美元至230000美元。在40至59岁的男性中，成本效益递增的排序为：戒烟（每LYG 2608 - 3738美元）；中度和重度高血压治疗（每LYG 8564 - 38678美元）；轻度高血压治疗（每LYG 11906 - 59840美元）；饮食治疗（每LYG 16143 - 20158美元）；以及高胆固醇血症的药物治疗（每LYG 33850 - 81010美元）。在女性中，排序为：戒烟（每LYG 4482 - 5756美元），中度和重度高血压治疗（每LYG 9585 - 57983美元），轻度高血压治疗（每LYG 15248 - 86075美元），饮食治疗（每LYG 57175 - 62154美元）；以及高胆固醇血症的药物治疗（每LYG 104100 - 259150美元）。
