Epler G R
New England Baptist Hospital, Boston, MA 02120, USA.
Curr Opin Pulm Med. 1998 Mar;4(2):93-7. doi: 10.1097/00063198-199803000-00006.
Reports of the characterization and understanding of bronchiolitis obliterans organizing pneumonia (BOOP) have continued at an accelerated rate for several years. The radiographic and high-resolution CT features of BOOP continue to be documented. There have been new insights into the pathogenesis of BOOP. An animal model has been developed. Video-assisted thoracoscopic biopsy has become a standard for confirming the diagnosis. Childhood BOOP has been described in several reports. Idiopathic BOOP continues to be the most common type; however, a variety of clinical settings such as inhalation of mold spores and associated disorders such as renal transplantation continue to be described. This paper provides an update of advances in the pathogenesis, radiographic features, clinical course, and categorization of the heterogeneity of BOOP.
关于闭塞性细支气管炎伴机化性肺炎（BOOP）的特征描述及认识的报告在过去几年持续快速增加。BOOP的影像学及高分辨率CT特征仍在不断被记录。人们对BOOP的发病机制有了新的认识。已经建立了动物模型。电视辅助胸腔镜活检已成为确诊的标准方法。多篇报告中描述了儿童BOOP。特发性BOOP仍然是最常见的类型；然而，诸如吸入霉菌孢子等多种临床情况以及诸如肾移植等相关疾病也不断被报道。本文对BOOP的发病机制、影像学特征、临床病程及异质性分类方面的进展进行了更新。
